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Can anyone reccommend hydoxy b12 and a b complex?

helen1

Senior Member
Messages
1,033
Location
Canada
Too bad about the pyridoxine form of B6 in there with not nearly enough p5p. Also maybe not enough niacinamide. You'd have to supplement with B12 in another form anyway, sublingual or whatever, as the oral route provides little absorbable B12.
You might not have enough folate in there either.
I haven't found the perfect b complex, so take them separately. But appreciate looking at any possibilities!
 

helen1

Senior Member
Messages
1,033
Location
Canada
The pyridoxine form of B6 requires a conversion step, which some of us won't be able to do. It converts into P5P, which is bioavailable. That's why a lot of us take P5P. I read a study which showed a lot of Irish people have that inability to convert and theorized it may be related to alcoholism.

There's also something about pyridoxine being toxic at not terribly high doses, but can't remember the details.

And enteric coated appears important for P5P.
 

caledonia

Senior Member
I like the liquid sublingual B12s. Yasko sells hydroxy and adenosylcobalamin. They're mega drops (1000mcg per drop), so you'll likely need to dilute them down with water.
http://www.holisticheal.com/adenosyl-12-mega-drops.html
http://www.holisticheal.com/hydroxy-b12-mega-drops.html

She also has some lozenges, but I can't vouch for how well they absorb.

Ben Lynch has a nice looking B complex - low in B6 for those with CBS mutations, no "folic acid" like Yasko's. Haven't tried it personally yet.
http://www.seekinghealth.com/b-complex-supplement.html