ljimbo423
Senior Member
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I agree, but it's not as simple as taking an immunosuppressant. I've tried several that had no effect on my symptoms. It might be necessary to suppress one cytokine and support another. Maybe it's necessary to do both of those things and modify the HPA axis in a particular way.
I agree and what makes it all the more confusing to treat, is that many or most of us seem to have different cytokines that are high or low.
I was able to trigger temporary remissions in the first few years, so it isn't impossible to do it. I expect it would take more effort to trigger remission now. It might take several drugs, supplements, and whatever else to 'set the foundation' for something else to trigger remission.
I get the feeling that many of these dysfunctions support each other. I think the immune dysfunction is the first domino to fall so to speak. Causing all the other dysfunctions but the other dysfunctions' like mitochondrial dysfunction, oxidative stress, gut and brain dysfunctions.
Play some role in maintaining the immune system dysfunction, if that makes sense. Causing to some degree a self sustaining cycle. Also, as you say, the low grade brain inflammation (HPA axis etc.) could also be causing dysfunctions in the body, helping to perpetuate them.