Blood clots continue to wreak havoc for patients with severe COVID-19

Treeman

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Another piece of research discovering micro clots in the blood

Blood clots continue to wreak havoc for patients with severe COVID-19 infection, and a new study explains what may spark them in up to half of patients.

The culprit: an autoimmune antibody that’s circulating in the blood, attacking the cells and triggering clots in arteries, veins, and microscopic vessels. Blood clots can cause life-threatening events like strokes. And, in COVID-19, microscopic clots may restrict blood flow in the lungs, impairing oxygen exchange.


New Cause of COVID-19 Blood Clots Identified (uofmhealth.org)
 

gregh286

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The technology used to uncover the clotting is groundbreaking tech only available in research labs. Pretorius discussed this in one of her recent articles. The tool is only available to a few labs at present.
Fair enough.
I remember a few researchers saying cells were sticky....Ron Davies mentioned it in past.

Could be clotting due to stickiness.
Clumping together by accident..as opposed to a body decision.
 

BrightCandle

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Finding it in the plasma under fluoresence is new but actually a couple of researchers have pointed out now you can see the blood is clumping on a basic student microscope with no processing at all, its clearly wrong the moment you look at it. Joshua liesk was showing this earlier this year on ME patients, covid long haulers and after the vaccine! So while the fluoresence test is new(ish) it does appear ME shows obviously in blood clumping and all ME blood is presumably sticky as a result.
 

SWAlexander

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I wanted to know more about blood clots after I had my last lab test. I read "Protein C helps regulate blood clots and is vital to the process of wound healing. A shortage of protein C can lead to abnormal blood clots and other, serious conditions."
After, I watched this:
 

Sancar

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:music:@Treeman @SWAlexander ~ Thank you both for this IMPORTANT information!!!
Blood clots are tricky. In this day Pademic hysteria, it all too easy for a Doctor to “brush it off” and not bother to look for “clotting issues”.
I have had a small knot in my calf since a bad accident/fall 11/2020. After my single Covid vaccine shot in May 2021 (which I have never recovered from) it has gradually gotten larger and larger. My PCP will still not see patients in person. She tells me to go to ER. I won’t. The local ones where I live are a petri dish jamed with the REALLY sick in a highly contagious environment.

I truly appreciated the video! I am going ask my ‘Specialist Dr’ for a test regarding the “proteins” to see if that will indicate something?

Again Thank you for your posts!!! :bulb:
 
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Not being funny but wtf have cfs research being doing that missed clotting ?
Surely this would have been obvious under serum examination
I've been wondering about the same, a lot...
Researchers have been looking to coagulation in ME/CFS. Prof. Scheibenbogen's theory about autoantibodies targeting coagulation and using plasmapheresis is one example. Sticky blood findings, endothelial damage and erythrocyte deformability also pointed to coagulation problems.

I've been reading a lot about hematology and blood analysis in the last months, trying to understand how no one had looked at PPP with a microscope before. The fact that you can't find plasma micrographs to compare ANYWHERE it's completely surreal for me (if anybody finds something, please tell me, I'm still looking).
The thing is, in theory, you shouldn't be capable of seeing anything in plasma with a microscope, just a transparent liquid. Proteins are too small to be visible, so no one was actually looking.

Every doctor I've talked to is very aware of microclots and the effect they'd have on the body. It's a very know physiological process, but the only way to see them was thought to be postmortem.

What is "newish" (2016) is the amyloid folding mechanism of fibrin that Resia Pretorius and Douglas Kell described in this article: https://www.sciencedirect.com/science/article/pii/S0079610716300499.
And that's what you can see with a fluorescence microscope and ThT.

We'll know a lot more in the upcoming months about clotting and its relation with ME/CFS, if any.