Bhupesh Prusty: "we are on a perfect path for identifying potential transferable factors in ME/CFS blood that can cause mito dysfunction..." GoFundMe

[Rufous McKinney]

In the slide the blue blob (mystery molecule is DAPI )

We were previously told the blue organ is a cell nucleus. Is that incorrect?

That would contain lots of DNA and would therefore stain blue...

 

[wastwater]

https://www.healthrising.org/blog/2019/04/15/nih-chronic-fatigue-lipkin-davis-prusty-oh/

A lot of this has been mentioned before along with other ideas

 

[Rufous McKinney]

A lot of this has been mentioned before along with other ideas

thank you for posting this as it explained far more than the rumors on this thread.

 

[raghav]

We were previously told the blue organ is a cell nucleus. Is that incorrect?

That would contain lots of DNA and would therefore stain blue...

Edited -
DAPI (pronounced 'DAPPY'), or 4′,6-diamidino-2-phenylindole, is a fluorescent stain that binds strongly to adenine–thymine rich regions in DNA. It is used extensively in fluorescence microscopy.

So the mystery molecule must be sncRNA U14

I think the mystery molecules are sncRNA U14, Human U6 snRNA and the last one on the screen says Scrambled RNA(Dont know what he means by that- Is it varying from person to person)

 

[raghav]

Only after seeing the published paper will we know the comprehensive list of molecules that Prusty has identified.

 

[raghav]

https://twitter.com/i/web/status/1237812974846464000

 

[Badpack]

@raghav didnt he promise to publish till the end of the month ? im confused now.

https://twitter.com/i/web/status/1231185630966796288

 

[RL_sparky]

@raghav didnt he promise to publish till the end of the month ? im confused now.

https://twitter.com/i/web/status/1231185630966796288

@Badpack

He has a paper that is in revision and will be out soon. The next paper with the first identified factor will follow after that.

 

[RL_sparky]

CMRC 2020 Bhupesh Prusty's presentation

 

[lauluce]

sooo... did this guy actually cracked at least a portion of ME/CFS cases? is this a world first?

 

[lauluce]

So why do you think it's only 40% of M.E patients and not higher?

I think it's because I always though was going to be the case: "ME" is actually many diseases

 

[xebex]

I think it's because I always though was going to be the case: "ME" is actually many diseases

I think it’s one disease triggered by different viruses that cause the same problem. I imagine they will find similar results with CMV and EBV I wonder if they have already looked for these In The same place they are finding the HHV6.

 

[Rufous McKinney]

CMV and EBV I wonder if they have already looked for these In The same place they are finding the HHV6.

Do we know anything about how they stain for these viruses?

 

[Rufous McKinney]

CMRC 2020 Bhupesh Prusty's presentation

So that is Amazing and Nobel Prize nominating worthy if anybody were to ask me.

QUESTION..any thoughts on: this antiviral phenotype...can anyone better explain this.??..is he saying we tend to NOT succumb to viruses the way normal healthy people would?

 

[Rufous McKinney]

I think it’s one disease triggered by different viruses that cause the same problem

We've been shown that various viruses share genetic codes that facilitate their- take over. So its likely these various differing viruses may have similar effects...

Wonder if different viruses tend to invade different tissues...that might result in- TYPES of ME expression.

 

[xebex]

@Rufous McKinney absolutely! Or the different viruses cause a slightly different immune response which could be why some people have this antiviral response and others catch everything! The new ground prusty and others are uncovering is astonishing! And mainly going unnoticed in The rest of the medical world!

 

[Rufous McKinney]

Or the different viruses cause a slightly different immune response which could be why some people have this antiviral response and others catch everything!

It would sure be nice to better understand this antiviral phenotype thing- at the moment we have this new corona.....

 

[Rufous McKinney]

The new ground prusty and others are uncovering is astonishing! And mainly going unnoticed in The rest of the medical world!

It does seem hot off the press..plus no Press Yet (waiting for actual publication).....

With all this interest in viruses at the moment, you'd think we could more effectively somehow PR ourselves and hitch together our wagons....

 

[Mary]

Wow! Starting at 4:48 on Prusty's video, he explains why people with ME/CFS don't get the flu! The flu is a fast-growing virus and our cells (ME/CFS patients) lack the nutrients necessary for the virus to grow! I wonder if this is applicable to COVID-19? We may have a natural immunity of sorts - too sick to get sicker!

 

[xebex]

@Mary yes it’s fascinating! Explains why I don’t get sick for sure! Weren’t we talking about this in another post? Now my question is are the people who get sick all the time suffering with a differnt variation of ME/ virus or are they confusing their “sickness behaviour” for catching something.