BHMT-02,BHMT-08 ++ Behaves like CBS+ meaning?

[Seven7]

Can somebody explain to me what does this mean that


BHMT-02, 04, and 08 heterozygotes may behave like CBS +

So when I read the combinations for CBS should I read the one that says CBS+ even though mine is -- ??? I am allergic to Sulfa.

http://www.heartfixer.com/AMRI-Outcomes-Non-CV-Autism-Methyl Cycle.htm


My info in case needed, and reference material

BHMT Gene

• rs585800 - BHMT-01 (Risk Allele: T)
• rs567754 - BHMT-02 (Risk Allele: T)
• rs617219 - BHMT-04 (Risk Allele: C)
• rs651852 - BHMT-08 (Risk Allele: A, 23andMe: T)

The product the BHMT gene is central to the ‘short cut’ through the methylation cycle, again helping to convert homocysteine to methionine. The activity of this gene product can be affected by stress, by cortisol levels and may play a role in ADD/ADHD by affecting norepinephrine levels.

Yasko believes that believes BHMT-02 and BHMT-04 play a role in the gut environment. Yasko also believes that BHMT-08 is related to the impact that psychological stress has on a patient's attention levels.

Gene Position SNP Versions Genotype

BHMT 78409060 rs651852 C or T
TT

BHMT 78409987 rs492842 C or T
TT

BHMT 78410145 rs6894156 C or T
CC

BHMT 78410564 rs6875201 A or G
AA

BHMT 78413504 rs3797546 C or T
TT

BHMT 78416416 rs567754 C or T
TT

BHMT 78421894 i6055405 A or C
CC

BHMT 78421959 rs3733890 A or G
GG

BHMT 78421959 i6060841 A or G
GG

BHMT 78426969 rs59109725 C or G

 

[Valentijn]

BHMT 2 and 4 do nothing, and BHMT 8 has a very minor impact. So I suppose that is like CBS +/+, since the Yasko tested CBS SNPs also do very little or nothing

 

[hugh_jass]

BHMT 2 and 4 do nothing, and BHMT 8 has a very minor impact. So I suppose that is like CBS +/+, since the Yasko tested CBS SNPs also do very little or nothing

@Valentijn ,Hello, Ive seen you say this before in another thread about CBS and BHMT not being important. Is it just because Yasko said it (Ive read she did screw up the CBS) or do you have scientific literature to back that up? The reason I ask is I just got my 23&me results results and Im:

HOMOZYGOUS

BHMT-02
BHMT -04 (Not Found)
BHMT-08

HETEROZYGOUS

VDR Bsm
VDR Taq
ACATI-02
MTHFR 1298C
MTRR A66G
MTRR A664A
CBS 699T
CBSA360A

So Ive been scouring the internet for information in hopes that I may actually feel better one day. But if what you say is true, I just wasted a lot of time researching and money on supplements because my snp's are nothing to worry about. Can you please clarify?

 

[Valentijn]

Is it just because Yasko said it (Ive read she did screw up the CBS) or do you have scientific literature to back that up?[/USER]

Do a search is this forum. 3-letter words like "CBS" won't work as search terms.