I so appreciate your willingness to be of help, Freddd, but you know very little about my own timing/terrain/medical history, so to conclude that the MCS is a symptom of methyltrap from GSH might be premature, imo.
Hi Leela,
Yes, it is just a possibility. That is why I asked you which other methyltrap symptoms you had so that it can be understood in your context. Instead of saying "none" or "none I'm willing to list" or "none of your business" are all perfectly normal answers along with actually listing the symptoms if any. Instead you do an avoidance implying perhaps all sorts of things. Only you know why. Several years ago it was much foggier. Learning to turn methyltrap on and off with a switch (glutathione), was most educational. It doesn't require glutathione. That was a learning experience of what makes glutathione so dangerous.
I had decades of MCS, all home grown from folic acid and CyCbl. It was for many people clearly connected in some way to methylation block, usually the most severe type, methyltrap or methyltrap and partial ATP block.. Multiple episodes in me and others, of turning it ON and OFF in a matter of days or weeks and always accompanied by "the usual suspects" listed below. MCS is not typically a mild symptom of partial methylation block. It is a symptom of severe methyl block It is instead frequently a "symptoms set" that is usually accompanied by some of the other folate deficiency symptoms like asthma, allergies, widespread body inflammation, brain fog, emotional changes, and in general the symptoms of FMS/CFS/ME.
A person with MCS from methyltrap will often have often 100 to 200 other symptoms as part of the general symptoms. People who have MCS with those other symptoms often have extreme responses to active b12s and active folate. MCS can be relieved in days to months after methylation and ATP startups. Of course if you are a person who hangs around with a bunch of people with FMS/CFS/ME symptoms because they are so lively and fun and you have only MCS, then you would be very unusual.
So how many causes of MCS do you know of? What are they? And knowing those causes you of course know how to reverse it then? Let's exchange information and chart out these other pathways. At least I can offer one interpretation and possibility of known cause and known reversal pathway. One person, me, is just one person. However, I have had reports from a lot of people who have been amazed at how fast this bane of their existence can be corrected with Metafolin and MeCbl/AdoCbl. Of course they had many of these other symptoms too so it was a real good bet on their part. In this game of YOU BET YOUR LIFE only you can decide what bets to play and what strategy to use.
So my best suggestion is find others who have healed from MCS and ask them how they did it. There are lot's of theories. How many of them have you found that had worked multiple times on multiple people in a predictable way? For it to be predictable one needs to match up the group of symptoms. Predictions are very specific things. In looking for "cures" from MCS I just haven't found any but then mine diminished after MeCbl and went away completely after I started Metafolin. Then it came back with a vengeance with glutathione and went away rapidly this time with a few days of 16mg/day of Metafolin, along with ALL the other folate deficiency symptoms I had. Currently I literally don't have any folate deficiency or insufficiency symptoms. I take no asthma meds, no allergy meds, no anti-inflammatories besides AdoCbl, MeCbl and Metafolin. I have no MCS, no massive widespread food sensitivities, no IBS, none of the symptoms listed below.
I wish you the same success in figuring out and dealing with your problems. I've spent 35 years figuring this out, working in a business that gave me raw access to mega-person data bases in total. Good health to you.
Group 2a - Both
IBS – Diarrhea alternating with constipation, IBS – Normal alternating with constipation
Group 2b – Either or both
Headache, Increased malaise, Fatigue
Group 3 - Induced and/or Paradoxical Folate deficiency or insufficiency
IBS – Steady diarrhea, IBS – Diarrhea alternating with normal, Stomach ache, Uneasy digestive tract, increased hypersensitive responses , Skin rashes, Increased acne, Skin peeling around fingernails, Skin cracking and peeling at fingertips, Angular Cheilitis, Canker sores, Coated tongue, Runny nose, Increased allergies, Increased Multiple Chemical Sensitivities, Increased asthma,
rapidly increasing Generalized inflammation in body, Increased Inflammation pain in muscles, Increased Inflammation pain in joints, Achy muscles, Flu like symptoms, Depression, Less sociable, Impaired planning and logic, Brain fog, Low energy, Light headedness, Sluggishness, Forgetfulness, Confusion, Difficulty walking, Behavioral disorders, Dementia, Reduced sense of taste, Increase irritability, Loss of reflexes, Fevers, Old symptoms returning, Heart palpitations, Bleeding easily.