So I've been seeing many posts about over methylation, undermethylation, methyl donors, and supplements that increase it or decrease it. I'm sort of confused as would this type of thing only apply to people who have trouble methylating such as the MTHFR defect? Do people who don't have this defect not have to worry about methylation? Or does having CFS cause even normal people to have problems with their methylation pathways regardless of genetic defects? I'm new when it comes to this methylation stuff so I don't know if this is common knowledge. Thanks.