They were not scientific, but I think the important relevance of their observations goes to show the limitations of looking at a topic like vaccinations from only the relatively narrow viewpoint of science alone.
This issue of turning intuitive, empathic observations into scientific measures is a difficult one. When my Coxsackie B4 virus spread to over 30 friends and family, I observed it caused a lot of overt physical and mental disease, such as sudden heart attacks (one which was fatal) and viral myocarditis in the previously healthy, and mental conditions such as generalized anxiety disorder and depression.
In two people the virally-induced depression and mental changes were so severe that they left their jobs and their social lives and literally became hermits; they cut off from most of society. One actually went to live a hut he built in the forest. That's a serious mental state change.
Those kind of overt, serious mental and physical illnesses you can measure scientifically in studies (and I would love to see more studies performed on coxsackievirus B and the diseases it may trigger). But I noticed there were also some subclinical changes my virus produced in most people who caught it — subtle subclinical changes that are much harder to measure using scientific methods.
I noticed that nearly all who caught my virus developed permanent but subclinical personality changes. Personality changes like becoming more irritable, less emotional, more sensitive to stress, less sociable and more insular, less tolerant of the views and opinions of others, etc.
I hate to see humanity oppressed or afflicted by factors which make them less what they could be, that make them less than the bubbly, emotional, wholesome and spiritual people they should be. So it pains me that this virus I caught is not only causing serious physical and mental diseases in around 10% who catch it, but also a detrimental subclinical degradation in personality qualities in nearly everyone who acquires this virus.
And this virus is traveling freely around the world, and likely infecting millions of people, reducing their humanity, and reducing the quality of their lives.
But if you want to get the attention of the scientific community, you need to prove what I observed in using objective scientific measures. That can be very difficult. Some things can be easy to perceive intuitively (if you are the empathetic type), but hard to measure in an objective scientific way.