Yes, I am very happy to see these things coming together! As I have been posting lately, it makes a lot of sense from biochemical and genetic standpoints that oxidative stress, glutathione depletion, and a methylation deficit would be connected with the retroviruses. Some sort of combined treatment does seem to make sense to me, too.
A small point: I think there is an error in the transcription of what she must have said (I wasn't able to be there). I think she must have said "methylfolate and B12" rather than "methofolate in B12." Methylfolate (or 5-methyl tetrahydrofolate, aka 5-MTHF, Metafolin, FolaPro, MethylMate B, and Deplin) is one of the key supplements in the methylation-type treatments, of which there are now several being used. B12 is the other most important component.
Note that she specifically mentioned the prescription "medical foods" Deplin (listed above) and Cerefolin. Cerefolin is actually Cerefolin-NAC, and it contains
methylfolate, methylcobalamin (the methyl form of B12), and N-acetylcysteine or NAC. Conventional physicians are more likely to use these, because they are FDA prescription treatments. The same ingredients are available over-the-counter, probably at lower cost, but the prescription treatments may be covered by insurance if the doctor is able to specify an appropriate code for the diagnosis. Deplin contains 7.5 milligrams of methylfolate, which is a very big dosage compared to the few hundred micrograms we have been using for ME/CFS treatment, and a dosage that large could cause some strong detox symptoms.
It's interesting to note that Cerefolin-NAC and the methylation treatments in general are still running fairly high on the average effectiveness ratings at the crowd-sourced CureTogether site, though they have dropped back some in the rankings: http://www.curetogether.com/chronic-fatigue-syndrome/treatments/
I think the factor that keeps them from rising even higher in the rankings is the detox symptoms they provoke. When some of the people find these intolerable, they tend to stop the treatment, and report that it made them worse. I can certainly understand this response. How is a person to know whether it is going to help them eventually, if it makes them worse initially? However, people who have lowered the dosages and stuck with the treatment have mostly had good results.
More information on the methylation treatment is available at www.cfsresearch.org
by clicking on CFS/M.E. and then on my name, or by going to your site at http://www.aboutmecfs.org/Trt/TrtGSHIntro.aspx
With regard to gcMAF, I would refer you to thread on that here on the forum. This is sounding very promising. Dr. de Meirleir is reporting good results with it, and Dr. Cheney is moving in that direction now, too. Basically, it involves modifying a protein found naturally in the body and putting it back in. The gc protein is the vitamin D receptor protein. With a couple of modifications, this protein acts as the main activating factor for the macrophages, which are the "big swallower" white cells of the immune system. Using gcMAF (discovered by Yamamoto) is a way of inducing the person's own immune system to go after pathogens and tumor cells. It has been used in prostate cancer and in HIV, to good effect. It's difficult to get this treatment in the U.S. at present, but I understand that efforts are being made to change this. If this treatment continues to work as well as has been reported, I think it has the potential to be used for other diseases beside those treated so far. This could be a very big thing.
Thanks to Lannie and to you for this report.