Are CellTrend tests reliable as an indication of autoimmunity?

Pearshaped

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This recent study finds no differences in GPCR autoantibody concentrations between patients with POTS and healthy controls when using CellTrend tests (ELISA).

https://ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.122.059971

This seems to suggest that CellTrend tests may not be useful to establish the role of autoimmunity in POTS.
I guess you are right there, but Im no expert.
Re: autoimmunity are Anti nuclear Antibodies (ANA) one of the more reliable hints that auotoimmunity is present.
 

Gingergrrl

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Re: autoimmunity are Anti nuclear Antibodies (ANA) one of the more reliable hints that auotoimmunity is present.
ANA is a reliable test that shows the presence of autoimmunity but it does not show a specific disease. Often if the ANA is positive (the ANA titer and pattern), then the lab automatically tests you for a bunch of other specific autoantibodies.