mariovitali
Senior Member
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I would like to share a post from my blog that involves Apigenin. The software i use identifies it as an interesting research target. Apigenin can be found in chamomile tea and parsley.
Some interesting excerpts, possibly relevant to PwME :
Original post :
http://algogenomics.blogspot.com/2019/01/apigenin-proposed-research-target-for.html
Some interesting excerpts, possibly relevant to PwME :
-Significantly decreased insulin resistance, blood glucose
-Significantly decreased inflammation by inactivating NF-kB and reducing pro-inflammatory mediators such as MCP-1, TNF-α and IL-6
-Decreased hepatomegaly and lipid droplets, indicating beneficial effects on NAFLD.
-Decreased plasma free fatty levels
-DAVID Functional annotation clustering identified that the majority of hepatic genes regulated by apigenin in HFD-fed mice were related to oxidative phosphorylation (OXPHOS), the electron transport chain, the tricarboxylic acid (TCA) cycle, fatty acid metabolism and cholesterol homeostasis.
-Increased genes that facilitate fatty acid oxidation
Original post :
http://algogenomics.blogspot.com/2019/01/apigenin-proposed-research-target-for.html