This is not my thread, so please forgive me, but I’d like to make a suggestion...
Could those posting please state whether or not they were diagnosed with SIBO, from breath test or symptoms,
and if known, what type (hydrogen/ methane)? And how long did you the take the medications? It would help to see if we can piece together a pattern of successes and failures.
For example, I was given xifaxan for one week years ago by a gastrologist on a guess of sibo. It made me terribly ill, worsening all symptoms. There was no benefit. Later was told that I didn’t take it long enough. Not knowing what type I may have, I made myself very sick for nothing.
Breath tests aren’t perfect either, in some cases it may be necessary to treat by symptoms. But in my case, my symptoms match more with methane, so xifaxan alone is probably a dud.
It is reported that xifaxan alone is about 50% effective on hydrogen SIBO, but a xifaxan/ neomycin combo is 85% effective on methane SIBO.
I've read very few cases where script meds alone were effective for long term treatment. Herbs and supplements like neem, Berberine, and allicin are needed.
I’ve posted this elsewhere, but if you haven’t already seen it take a look...
https://chriskresser.com/an-update-on-sibo-research-with-dr-mark-pimentel/
There’s a third SIBO type, hydrogen sulfide, that has turned up. It’s more difficult to treat, but apparently bismuth is used.
There is an additional test, that looks at food poisoning antibodies. Again, I’ve posted this elsewhere, but if you have or suspect SIBO with IBS-D, might be something to look into...
https://www.ibssmart.com/
I just did one, came back negative.
In Esther’s case, the xifaxan worked wonders, but there are additional things that could be helpful long term.