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Anyone tried DMG?

Celandine

Senior Member
Messages
201
I came across this the other day and it looked like a potentially interesting supplement to try. Couldn't find any mention of it on here.

Info from ProHealth:
"N-Dimethylglycine (DMG) is a nutrient found in the cells of every plant and animal. DMG is one of nature’s ways of getting the most out of the aerobic, oxygen-consuming, mode of respiration. DMG is a natural nutrient, found in many plants and produced in the body’s higher organisms. DMG has been shown to aid in the transport of oxygen across the cell to the mitochondria, small organelles within the cell, where energy reactions take place. By making more oxygen available for aerobic respiration, DMG delays the buildup of lactic acid in the muscles and mitigates the severity of the conditions resulting from it.

DMG plays a crucial role in the respiratory cycle of the cells, transporting oxygen and serving as a potent methyl donor. A larger nutrient complex containing DMG was the subject of numerous studies in the US, Europe and the Soviet Union during the 1950’s and 1960’s. This work led to its adoption as part of the dietary regimen for Soviet athletes. In the mid-1970’s, the American biochemist Dr. Roger Kendall identified DMG as the key ingredient of previous formulas. Since then, DMG has become a favorite nutrient for amateur and professional athletes as well as many clinicians throughout the world. Research at several American universities has demonstrated DMG’s usefulness in a variety of species, including the horse.

Numerous tests performed with humans and horses have documented DMG’s oxygen transporting role and the effect it has, both on performance and on recovery time following a strenuous workout. The longer the aerobic cycle can be maintained or the more prevalent it is during the exercise, the less waste products there are to build up in the system, since aerobic respiration produces no harmful wastes. Moreover, DMG is a natural substance found in the body and has never been shown to have any deleterious metabolic activity.

DMG in the body is primarily a product of cellular action. Dietary supplementation makes additional DMG available to cells throughout the body. DMG is a water soluble nutrient and is readily absorbed, but it is constantly broken down as it is used in the mitochondria and should be fed twice daily."
 

Mary

Moderator Resource
Messages
17,293
Location
Southern California
@Celandine - I took DMG at one time, it seemed to help my energy and I can't remember why I stopped taking it. It did cause my potassium to tank, just like folate did. I had to add in extra potassium and the symptoms went away.
 

Celandine

Senior Member
Messages
201
@Mary Hmmm. Daughter is already on liquorice, which is a crucial thing for her, but also depletes potassium, so maybe this won't be a great fit. Or maybe she'll just need to supplement potassium. Or maybe her potassium won't drop because she is so tilted towards potassium over sodium. Everything always such a puzzle! I'll put DMG on the long list of things we might try one day. Good to hear you found it helpful at one time.

Just started her on PEA today (I know, totally different action and purpose) and will see how we get on with that for a while. Tend to add one at a time now otherwise it all gets very blurry. It's funny you say you can't remember why you stopped taking it. I have a cupboard full of that kind of thing. I can't remember why it was a good idea in the first place or why it didn't work. Have to research all over again to figure it out usually.
 

perchance dreamer

Senior Member
Messages
1,686
I really like PEA. My doctor recommends it for neuroinflammation. I take it after dinner because it makes me sleepy if I take it at breakfast. Take PEA with food for best absorption.
 

Celandine

Senior Member
Messages
201
Oh, interesting @perchance dreamer . I didn't think it would have an obvious effect like drowsiness. I was thinking it would be one of those things you take for a long time and only looking back notice it's made a difference. It would be a real bonus if it made daughter drowsy at normal bedtime. Insomnia is one of her big issues.