Anyone have pos or neg effects from a magnesium supplement on mcs/mcas?

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I haven't tried a magnesium supplement in a few years. My doctor just recomended that I try it, but im a bit hesitant. I'm now one of those hypersensitive types (i have pretty severe mcas, REALLY bad in the gut) and it seems like, from my research on how certain minerals can activate trp's and the pi3k pathway (which i do extremely well on supplements that inhibit it), magnesium might activate things and make my chemical sensitivities worse. Or, it could displace calcium and make things better. I can usually get an accurate idea of how i'll respond to something by digging through studies and such, but the waters are pretty murky on this one.

So, anyone have any substantial experience either way? If so, any other pertinent details would be appreciated.
 

Learner1

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I have MCAS and have taken magnesium for years with no issues, though I react to other things.

It does come in cream form for application to skin if you think that might be better.