Any advice? Methylation stopped working.

LisaGoddard

Senior Member
Messages
284
HIi,
I've been on the simplified methylation protocol for over six months and experienced great improvement in my inflammtion symptoms but needed to take LOTS of potassium daily. Then a week ago, the inflammation returned and I stopped needing any potassium whatsoever even though I am still taking the folate and methylb12. Also I got some very sore ulcers on my tongue. Anyone with a similar experience or advice?
I have changed my Methyb12 bottle incase the last one was degraded. Still no response. Just can't think what might be the block?
Thanks,
Lisa
 

Crux

Senior Member
Messages
1,441
Location
USA
LisaGoddard;

Hi Lisa,
A first guess could be that more MB12 and or folate is needed.
Another guess is that if it's not too little, maybe it's too much. ( I only write this because, my mouth sores worsened when I took too much folate,though many people's cankers improve with added folate.) Mine improved when I increased B12.
The fact that you stopped needing potassium does seem like more may be needed. ( Personally, I would try more MB12 first, as a guess.)
 

dbkita

Senior Member
Messages
655
Did you change how you take it? For example vitamin C will destroy methylfolate in the gut before it can be absorbed.
On the other hand niacin or niacinamide will soak up methyl donors like a sponge.
 

LisaGoddard

Senior Member
Messages
284
Thanks for the suggestions. I am taking more folate and b12 to see if that is what is needed.
I do take vit c and high vit bs inlcuding b3 but it hasn't interfered before.
I'm feeling a bit better but still no need for potassium.
Thanks again
 
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