Well it's one of those things that are very intensely debated from what I've read. It all comes down to "proper" chelation. Andy Cutler says that the only safe way to chelate metals is low dosing of ALA and DMSA frequently so it doesn't little by little as opposed to a huge IV with large quantities that can mess you up. So if you were to ask the andy cutler followers, they would surely say no way jose as some of them even start off at 7mg of ALA.
however, it's hard uncover the objective truth behind all of it and frankly there is no objective truth, only relative and what works for you best I guess. My doctor has recovered many autistic children using DMSA IV use instead of cutler's protocol following certain standards. I also don't see how something like ALA can really mess you up unless something else is involved or you have lots of mercury? I'm not sure about this. there are TONS of people on the bodybuilding over taking NAC for recovery, ALA for antioxidants, etc. and its in multivitamins so one wouldn't even think to consider the amalgam aspect of it. I ordered a book by Dr. Berk Burkson who wrote "Alpha lipoid acid breakthrough" and it is really some amazing stuff, ALA hthat is. But because there is such a strong sentiment and opposition against taking even a little bit of ALA if you have mercury or amalgams by Andy Cutler, it has scared me a bit into doing some additional research. So far I haven't found much other than two views, a) do it, or b) do it and die.. (or run the risk of being messed up)