23andme results no MTHFR mutations (Help)

[uriraha8]

Hey
I have finally done the 23andme test.

This quite surprised me cause i was sure i had some mthfr issues but i don't.
I suffer from chronic fatigue and depression which antidepressants do nothing for it.

I found out i have some mtr/mtrr issues which as i read this mutation needs lots of methyl B12 which i already taking 1 mg daily.

Should i add methyl folate for it? although i don't have any mthfr mutation? Cause i feel a bit anxious when taking the methyl B12 alone.

I also have comt mutations should it be a problem? I understand people with comt mutations can't tolerate methyl groups very well.

Is there anything i can do with the VDR/Taq mutation? i have vitamin d deficiency but i can't tolerate high doses of vitamin d (it cause me migraine) i can only tolerate 1000IU daily.
Should i continue with the methyl B12 and methyl folate? or exchange it to hydroxy B12 base on my results.

Any help will do for me i really need it

Thanks

 

[UM MAN]

VDR Taq AA is not a mutation, it is normal.

There are a lot of MAO-A homo-z people on here with depression and anxiety issues,
but, so far there does not seem to be reified treatment.

 

[Valentijn]

@uriraha - I don't see any problems in those results. If you want to look at additional MTRR and MTHFR mutations which might have an impact, there's lists at http://forums.phoenixrising.me/index.php?threads/interesting-mtrr-variations.24551/ and http://forums.phoenixrising.me/index.php?threads/interesting-mthfr-variations.24543/

Additionally, there's a downloadable program at http://sourceforge.net/projects/analyzemygenes/ which pulls out your very rare results. SNPs starting with "i" instead of "rs", and homozygous results can be especially interesting.