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Hello guys, I'm a first time poster but a long time lurker here. I recently got my 23andme results back and put them through genetic genie. I needed some help interpreting them and where I should go from here.
"Here are your homozygous mutations as indicated in your SNP gene table above (not including MTHFR):
I have no MTHFR mutations (thank god). On my detox profile the only mutation that stood out was:
SOD2 A16V ra4880 AG +/-
My life long problems have been anxiety, energy drains, sometimes a severe mental fog takes over me and I can't even speak properly, the symptoms are eerily similar to my grandmas Alzheimer's and I really would like to avoid going down that path. Mental retardation, clouded thinking, extreme anger spells, irrationality depending on how anxious I am, speech impediments (this one hurts the most), and OCD.
Now, I dug up some info on several mutation websites including Yasko's research, and came down to several conclusions on supplements that could potentially make a difference
MAO-A R297R: Low MAO-A activity:
TAKE: b2, progesterone cream, 2mg copper, forksolin, extra virgin olive oil, ginko biloba
DONT TAKE: circumin, quercentin fish oil, and maybe resveratrol
BHMT-08:
-lower homocysteine with p5p
MTRR:
-low dose mb12 every few days (conflicting because I don't react well to MB12)
CBS:
-increase bh4, don't take coq10 because it's a lipid donor
BHMT:???
SOD2:
-progesterone cream
-magnanese
VDR:
-Sage
-Rosemary
To further complicate things, i also put my raw data through nutrahacker and it said I have homozygous mutations for COMT, GAD1 and a few other genes. This would explain why I don't react positively to mb12, but why were Genetic Genie's results much different?
If anyone can help me I'd appreciate it
"Here are your homozygous mutations as indicated in your SNP gene table above (not including MTHFR):
- MAO-A R297R
- VDR Bsm
- VDR Taq
- MTRR A664A
- BHMT-08
- CBS C699T"
I have no MTHFR mutations (thank god). On my detox profile the only mutation that stood out was:
SOD2 A16V ra4880 AG +/-
My life long problems have been anxiety, energy drains, sometimes a severe mental fog takes over me and I can't even speak properly, the symptoms are eerily similar to my grandmas Alzheimer's and I really would like to avoid going down that path. Mental retardation, clouded thinking, extreme anger spells, irrationality depending on how anxious I am, speech impediments (this one hurts the most), and OCD.
Now, I dug up some info on several mutation websites including Yasko's research, and came down to several conclusions on supplements that could potentially make a difference
MAO-A R297R: Low MAO-A activity:
TAKE: b2, progesterone cream, 2mg copper, forksolin, extra virgin olive oil, ginko biloba
DONT TAKE: circumin, quercentin fish oil, and maybe resveratrol
BHMT-08:
-lower homocysteine with p5p
MTRR:
-low dose mb12 every few days (conflicting because I don't react well to MB12)
CBS:
-increase bh4, don't take coq10 because it's a lipid donor
BHMT:???
SOD2:
-progesterone cream
-magnanese
VDR:
-Sage
-Rosemary
To further complicate things, i also put my raw data through nutrahacker and it said I have homozygous mutations for COMT, GAD1 and a few other genes. This would explain why I don't react positively to mb12, but why were Genetic Genie's results much different?
If anyone can help me I'd appreciate it