pasc

  1. junkcrap50

    Amsterdam scientists find an enzyme (IDO2) that could be the culprit of #LongCovid: Prolonged IDO2 activity & associated cellular stress in PASC.

    They found the IDO2 enzyme in "insane amounts" in Long Covid patients in all kinds of cells causing "a kind of collective suicide" as well as impaired mitochondrial function and Krebs Cycle dysfunction. They say it's clear that IDO2 continues to rage after the virus is defeated and IDO1...
  2. C

    Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells (Nikesjo et al, 2022)

    Abstract Post-acute COVID-19 syndrome (PACS) has been defined as symptoms persisting after clearance of a COVID-19 infection. We have previously demonstrated that alterations in DNA methylation (DNAm) status persist in individuals who recovered from a COVID-19 infection, but it is currently...
  3. C

    Preprint: Impact of cross-coronavirus immunity in post-acute sequelae of COVID-19 (Herman et al, 2022)

    Abstract Beyond the unpredictable acute illness caused by SARS-CoV-2, one-fifth of infections unpredictably result in long-term persistence of symptoms despite the apparent clearance of infection. Insights into the mechanisms that underlie post-acute sequelae of COVID-19 (PASC) will be critical...
  4. C

    Targeting the Monocytic-Endothelial-Platelet Axis with Maraviroc and Pravastatin as a Therapeutic Option to Treat Long COVID...(Patterson et al, 2022)

    Targeting the Monocytic-Endothelial-Platelet Axis with Maraviroc and Pravastatin as a Therapeutic Option to Treat Long COVID/ Post-Acute Sequelae of COVID (PASC) Bruce Patterson et al, 2022 Abstract Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of...