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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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midodrine

  1. M

    Could I easily make my own topical midodrine cream?

    I have midodrine pills (5mg), but do not want to take it orally anymore. I want to make what this paper is proposing: https://jamanetwork.com/journals/jamadermatology/fullarticle/2290938 "Midodrine, 0.2%, in a moisturizing skin cream (Vanicream) was compounded at the Mayo Clinic pharmacy and...
  2. M

    Addressing blood pooling

    Vascular dysregulation has been one of my most pressing Long covid symtoms. The worst part about it is the blood pooling in my feet. In the beginning I could sit up to work without issues. Around one year into the illness, I had one episode where I believe I overexerted myself, mainly my legs...
  3. Jenny TipsforME

    Midodrine and Lying Down

    I started taking midodrine yesterday. I'm after input from people who have ME and POTS and take midodrine. When you take it you're not meant to lie down for 4 hours. Now for me that's quite a long time to not lie down/put my feet up. Does taking midodrine at the right dose take away the need...
  4. Kyla

    Midodrine hydrochloride in symptomatic orthostatic hypotension: a double-blind, placebo-controlled, randomized, tilt-table study

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951503/ (open access)
  5. S

    How to take midodrine for POTS and still take a daily nap?

    My 23-year old daughter was diagnosed with neuropathic POTS. She tried Florinef, at 1/4 of the smallest dose, and she took it in the mornings, but she had terrible insomnia from it. It also took about 2 weeks for those side effects to fully go away. Her doctor recently prescribed midodrine...
  6. S

    Midrodine: how long did it take you to ramp up the dose?

    I've been prescribed midrodine for NMH and started off at 2.5mg plus sodium tablets, 3 times a day. That dose had no effect on my BP or symptoms after ten days so yesterday I was told to increase the midrodine to 5mg, 3 times a day. It didn't do much for my BP but it did seem to improve my...
  7. Gingergrrl

    Has anyone had Midodrine make them sedated like a sleeping pill?

    I couldn't find a thread on this particular aspect of Midodrine and really wanted to get some feedback. I was started on Midodrine by my new cardiologist in the hospital, first at 2.5 mg 2x/day and now at 5 mg 2x/day. The goal was to raise my BP (which is in the 80's/50's without Midodrine)...