inflammation

  1. Nord Wolf

    Chronic Lung Inflammation

    I’ve ben struggling with chronic lung inflammation for a handful of years now. My pulmonologist tabled it as Chronic Persistent Moderate Severe Asthma. What an absurd name. The consensus of my healthcare team is that the more severe development of ME/CFS caused the development of Chronic...
  2. I

    Link between POTS, MCAS and CFS - Innate inflammation in response to an antigen..t-cell exhaustion's role?

    31:00 onwards Dr Grubb explains which autoantibodies are found in POTS and suggests they are driven firstly by the innate immune system, including mast cell mediators and other cytokines, which then triggers the adaptive immune system to make autoantibodies . He argues it can't be coincidence...
  3. SWAlexander

    Gut Microbiota Dysbiosis Is a Crucial Player for the Poor Outcomes for COVID-19 in Elderly, Diabetic and Hypertensive Patients

    Excerpt: The possibility that SARS-CoV-2 infection of enterocytes modify gut microbiota is supported by the fact that some patients with COVID-19 present intestinal dysbiosis (16, 17). There is evidence that hospitalized COVID-19 patients exhibit a significant reduction in gut microbiome...
  4. daveu

    Fasting for reducing inflammation? (and hopefully neuroinflammation?)

    Hi there, My name is Dave. I currently present as about 65% on the ME Disability Scale. I recently read this excellent article about what we can do to keep our brain healthy and help reduce the onset & severity of dementia. I was interested in whether fasting can help brain health so I asked...
  5. SeanQHX1

    Opioids and Brain Fog

    Hi everyone again. For about 3 years I've been taking codeine (in the form of co-codamol) regularly every day to get relief from the continuous bombardment of severe brain fog and what I can only describe as horrible head feelings I've had non-stop, getting progressively worse since becoming ill...
  6. nerd

    Aberrations in the Cross-Talks Among Redox, Nuclear Factor-κB and Wnt/Catenin Pathway Signaling Underpin ME and CFS: A Review and New Hypothesis

    Aberrations in the Cross-Talks Among Redox, Nuclear Factor-κB and Wnt/Catenin Pathway Signaling Underpin Myalgic Encephalomyelitis andChronic Fatigue Syndrome: A Review and New Hypothesis Based on Results of Network, Enrichment and Annotation Analyses This paper is a preprint and it has not...
  7. MartinK

    Do sore throat / tonsil ulcers make you worse - PEM/inflammation?

    I realized one thing and I'm very interested. Before my ME/CFS started, I suffered also a lot from various upper respiratory illnesses - sore throat / tonsil ulcers / influenza. It often met me even when I was mild / moderate, not so much now, probably because Im at home at constant...
  8. Boba

    Help with Test Results

    Hi folks, I got some results from my immunologist and would like to ask you to help interpret them. It looks like my TNFa is very high supporting the theory of inflammation in my body. I had Covid 8months ago. Thanks!! Edit: I developed PEM and heavy fatigue after covid, which was in Nov 2020...
  9. Y

    Methylfolate causing inflammation behind nose?

    Brief Background: 31/Male, MTHFR A1298C GG, Anxiety, ADHD, I don't believe I have MS/CFS Both methyl-folate and folonic acid initially make me feel great, but then cause inflammation right behind my nose and seemingly in my general nasal/sinus tract. It also happens even with cofactors/methyl-B...
  10. nerd

    Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus

    Jog NR and James JA (2021) Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. Front. Immunol. 11:623944. doi: 10.3389/fimmu.2020.623944 Although this isn't about CFS/ME per se, this discussion shows the latest state of research on EBV causality with SLE. I think SLE...
  11. Pyrrhus

    Are Circulating Fibroblast Growth Factor 21 & N-Terminal Prohormone of Brain Natriuretic Peptide Promising Biomarkers in ME/CFS? (Domingo et al, 2021)

    A new paper looking at blood markers of oxidative stress and inflammation in ME: Are Circulating Fibroblast Growth Factor 21 and N-Terminal Prohormone of Brain Natriuretic Peptide Promising Novel Biomarkers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome? (Domingo et al., 2021)...
  12. B

    Meet The Scientist – Professor Jo Nijs

    Jo Nijs is a Professor of Physiotherapy at the Vrije University of Brussels, Belgum and a manual therapist at the University Hospital Brussels. He is holder of the Chair, ‘Exercise Immunology and Chronic Fatigue in Health and Disease’ at the Vrije University of Brussels created by the research...
  13. Jwarrior77

    Sore muscles everyday upon waking up?

    Basically every single day when I wake up all the muscles in my body are sore and fatigued. It's like I had just ran a marathon the day prior only I hadn't. They also feel inflamed as if the muscle tissue is breaking down. It usually subsides halfway through the day and then repeats again. I...
  14. frozenborderline

    Critiques of common conceptions of MCAS

    https://atomicchesterton.blogspot.com/2020/06/critique-of-concept-of-mcas.html?m=1
  15. SeanQHX1

    Brain symptoms still getting worse - Losing hope

    Hi everyone again. After looking through some old threads, I see that someone previously reported brain symptoms which are exactly like mine and couldn't have put it any better into words. This was after I spent years thinking that I was the only one in the planet with this mysterious brain...
  16. ChookityPop

    What is the most effective Anti-inflammatory non steroid agents/supplements?

    Hey gang, Maybe we could make a list of anti inflammatory agents/supplements? I want to know about sources thats not steroids like prednisone etc. Things I have tried is Bpc 157 Naproxen Vitamins Carnivore diet What are some of the most powerful anti inflammatorie properties out there?
  17. Sarah94

    Klimas' models of ME/CFS

    https://www.healthrising.org/blog/2019/10/02/powerful-models-predict-response-to-exercise-and-treatments-in-me-cfs/?fbclid=IwAR1LLNjH1FdLQhENJ57NHigfkBmYoGTMzEmq_0_HoPH3fG-Vm986xY71JEE
  18. M

    My face hurts.

    I have been having a lot more issues with my face recently. Since I got sick it has become pretty numb and randomly seems to "puff up." I have no idea what is causing it to swell or why, but when that happens its like skin on my face become ultra sensitive, like it hurts, and gets really red and...