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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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histamine

  1. Katy131

    Has Quercetin helped your sensitivity to allergies?

    I'm trying to find something (more/new) that will help reduce my sensitivities, particularly to foods, but also to fumes and chemicals in general in my MCS. I've read a lot about Quercetin in the last week, including both PubMed articles and anecdotal evidence that it helps both the histamine...
  2. T

    Quercetin metabolism, sulphur

    Hi all! I’m very confused and hope someone can help me. I really would like to take Quercetin for my MCAS but I also have hydrogen sulfide Sibo which causes sulfur intolerance. There’s conflicting information regarding quercetin becoming metabolite of sulphur in the body. When I message...
  3. chilove

    What could be causing sudden new symptom of weak and burning, aching muscles in my legs?

    Looking for suggestions on what could be causing a recent and sudden new symptom: Aching and burning and sore muscles in my legs? It started with my left knee suddenly giving out while I was walking but it didn't hurt, my knee would just sort of buckle. Then it progressed to that knee getting...
  4. SWAlexander

    Long Covid + Histamine / MCAS - Dr Tina Peers in conversation with journalist Nicola Haseler

    Full interview with Dr. Tina Peers on a possible cause of Long Covid symptoms.
  5. Shanti1

    Histamine as an inducer of symptoms in IBS

    Clinical studies support the hypothesis that histamine is an inciting factor in IBS for a sizable cohort. Antihistamine reduces pain in irritable bowel syndrome In a 12-week randomised trial, the team gave 28 patients the H1 antihistamine ebastine and 27 patients a placebo. Ebastine treatment...
  6. frozenborderline

    Dealing with major amounts of hypersomnia, need help

    So I had some episodes ofnhypersomnia pre surgery but they were more limited and different than what I'm experiencing now. My sleep wasnt usually deep in a refreshing way, I often felt unpleasant and like I was gasping for air when I woke up. It also was just less consistent hypersomnia and...
  7. M

    Long Hauler trying to prepare for a 24h urine test

    Hello MCAS folks, I am a Covid Long-Hauler. For a while I have been wondering if what I am experiencing is part of MCAS, given that is the case with many other suffering post-Covid. I DO NOT have the typical symptoms like hives, swelling, low blood pressure, syncope, diarrhea. I DO have...
  8. leokitten

    Betahistine

    Betahistine has been mentioned in passing in various posts but I thought it would be useful to make a dedicated thread to discuss pharmacology and possible effect on ME symptoms. Betahistine is typically prescribed for vertigo and other vestibular disorders. But in general it’s a strong H3...
  9. Jwarrior77

    Is This Considered Pressure Urticaria? Or Dermatographia?

    I've been wondering if anyone else experiences this. If I press my hand let's say on my face too long the area where the pressure was will turn very red. Not itchy or raised but a little hot. This can occur basically anywhere you apply pressure to not only my hands. Also if I scratch my skin the...
  10. J

    Burning GI, Rapid Weight Loss, Usually After B12 Supplementation

    I've got several health issues, but one of the most debilitating is states during which I experience 5/10 GI burning, burning throughout arms, hands, face, etc. and rapidly lose weight. These episodes seem to come up naturally, often after periods of stress or little sleep but are guaranteed...
  11. J

    Losing Progress, Looking for Next Step

    I've been dealing with health issues the past 6-7 years and while making some serious headway, I've recently started to backslide and am not quite sure of my next step. I'm starting to feel like I'm entering the final phase of my ability to manage symptoms and looking for a helping hand in...
  12. D

    My Sulfur Intolerance is managed with Quercetin. Please help me understand why.

    If I eat anything with sulfur in it my finger pip joints swell a little and turn a little red. Chicken effects me the most and eggs come in second. I have no idea why my finger pip joints swell but I believe it may have to do with uric acid or ammonia. Quercetin allows me to eat as much meat...