Search results for query: anhedonia

  1. A

    "Protesters so ill, they couldn't get arrested" - NY Times opinion piece 10-27-22

    Indeed! Here is two of the comments, the second one is the article author:
  2. K

    I need to sleep! Help !!!!!

    wow you may have explained why I have sudden severe insomnia. I have not taken my 3 brain sleep herbs for the last 4 nights, that includes lemon balm.
  3. S

    Bad reaction to 50mf TTFD thiamine (allithiamine)

    ...of negative reactions. I had an intense reaction-felt very wired and anxious, heart palpitations, and also now drop in mood + some anhedonia, the intensity has dropped somewhat but these are all still issues. I obviously stopped at one dose, but I'm wondering why I'm still feeling effects...
  4. Hip

    Amisulpride — A Multipurpose Drug for ME/CFS

    I found very low-dose amisulpride helped a great deal to reduce the irritability symptom of ME/CFS, but it does not do much for my anhedonia. But then anhedonia is almost impossible to treat. I don't know whether lowering or raising your amisulpride dose will help. I take 12.5 mg daily, and...
  5. Pyrrhus

    Feel like I’m watching myself from a distance

    ...ME/CFS and emotional blunting, apathy, anhedonia, depersonalization, derealization https://forums.phoenixrising.me/threads/me-cfs-and-emotional-blunting-apathy-anhedonia-depersonalization-derealization.80694/
  6. W

    B12 causing restlessness, anhedonia and sexual dysfunction

    I think you're unlikely to find an answer to that. The human body, and especially the brain, is composed of a vast number of interacting reactions, and those vary between individuals. That's why one person with ME benefits from some substance, and another PWME might have the opposite response...
  7. S

    B12 causing restlessness, anhedonia and sexual dysfunction

    ...like an adverse reaction to an antidepressant. Instant genital shrinking and total body numbness, as well as loss of emotions and bad anhedonia and dissociation. Do you Anyone else experince somethng similar? To other drugs or supplements and got better again? I had taken antidepressants...
  8. S

    B12 causing restlessness, anhedonia and sexual dysfunction

    ...do that causes such effects in the body? I just dont understand. I also have cognitive issues i Did not have before i started B12, and anhedonia. How does B12 cause anhedonia and loss of emotions? My whole skin is also less sensitive after the B12. How long does the effects of methylation...
  9. Hip

    Is there a link between Schizophrenia and Fibromyalgia and ME/CFS?

    ...mental symptoms I have with my ME/CFS are negative symptoms. The negative symptoms of schizophrenia are: Source: here My symptoms are anhedonia, blunted emotions, social withdrawal (and of course lethargy, like most ME/CFS patients). The only thing I have found to improve these symptoms...
  10. S

    B12 causing restlessness, anhedonia and sexual dysfunction

    ...badly. I dont understand what is happening and How. I keep getting restless and have bad sleep. Also get bad brain fog, concentration and anhedonia. The new symtom is sexual dysfunction. I had taken small doses B12 because of deficiency, and decided to try a larger dose again. Took it in...
  11. S

    Why are B12 supplements making my symptoms so much worse?

    Hi! Me again! I just wondered How B12 affects the brain. Does it cause depletion of dopamine? I get bad anhedonia and insomnia and restlessness when i take it. How does it affect neurotransmitters? Or is there another mechanism for this?
  12. acrosstheveil

    Why are B12 supplements making my symptoms so much worse?

    i've had all these symptoms from low quality b12. i think some are produced from black mold (Aspergillus Niger) and aren't purified enough. I get all these symptoms from toxic mold exposure as well. one of the worst offenders was Global Healing's B12. I almost had to go to the emergency...
  13. pattismith

    Anhedonia, attributed to deficit in reward processing, is a core feature in CFS, MD, chronic pain...Review 2022

    Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms - Henrik Heitmann, Till F M Andlauer, Thomas Korn, Mark Mühlau, Peter Henningsen, Bernhard Hemmer, Markus Ploner, 2022 (sagepub.com) Related thread...
  14. Z

    Alternative to acyclovir (bad reaction)

    Is famvir an hiv drug? If so, people take them for life
  15. Z

    Alternative to acyclovir (bad reaction)

    ...interesting, because my physical symptoms are mild and manageable, but since ( suspecte)long covid mental depression, depersonalization, anhedonia, has been absolute hell. Well I told dr Bansal that I had post viral fatigue in 2008. We went over my history until now. And he said he thinks...
  16. Hip

    High-dose manganese: could it be an effective treatment for ME/CFS? (Ron Davis Research)

    ...the last few days, I have been feeling terrible, much more tired, brain fogged, substantially more depressed, mentally frail, I have more anhedonia and I am even physically a little more weak. Whether this is due to the 20 mg of manganese I have taking daily, I am not sure because I have...
  17. H

    Those who have had COVID: did you experience anhedonia afterwards (reduced ability to find enjoyment from activities)?

    Interesting. I hadn't heard of this, but a friend of mine got COVID six months ago (practically asymptomatic). He always had a bit too little enthusiasm and too a bit too much ennui, but it seems to have been exacerbated. Never occurred to me that it might be connected.
  18. B

    Those who have had COVID: did you experience anhedonia afterwards (reduced ability to find enjoyment from activities)?

    I definitely developed more Anhedonia with Covid but also lost a lot of emotional range generally. Some of it has returned for spits and spurts and I have been almost manic in how I was pursuing pleasurable activities and then it would disappear. I didn't really have this problem before Covid at...
  19. Hip

    Those who have had COVID: did you experience anhedonia afterwards (reduced ability to find enjoyment from activities)?

    Has anyone found they are suffering from increased anhedonia after getting COVID? Anhedonia is defined as a reduce ability to derive pleasure or reward from activities that you previously found enjoyable. Anhedonia is caused by a dysfunction in the pleasure circuits of the brain, so that these...
  20. Springbok1988

    Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and… (Cash et Kaufman, 2022)

    ...significant reduction of fatigue and brain fog at just 100 mg a day. I tried ramping up with it but found the higher the dose, the worse my anhedonia became. At 500 mg a day I became depressed. I believe this has to do with reduction of glutamate from Glutamate Oxaloacetate Transaminase...
  21. M

    ME/CFS patient goes into remission after taking "elixir of youth" GDF11

    Yes, please share new substance for fellow guinea pigs ;-). Also, dosing of of GDF-11 and BPC-157. For me, reaching my upper fifties and finally getting a dx of Ehler's Danlos Syndrome and methylmalonic acidemia, I believe that EDS causes the perfect storm for so many problems that plague many...
  22. W

    Help with stool test results (Kleb/Pseudomonas)

    Just wanted to come in here and say my cfs was triggered by ssri as well. I’m rare in that I don’t have pssd (I’m female), but have anhedonia apathy and fatigue is the worst part. some are getting better by treating sibo as I’m sure you’ve seen. it’s interesting that so many develop pssd but...
  23. caledonia

    Why are B12 supplements making my symptoms so much worse?

    I've already posted links to my methylation documents twice. Please read them. I'm not sure if I have the chemical sensitivity info in there or not. The thing to try for that is a baking soda solution. Follow the antacid recipe on the box. It's something like 1/2 tsp in 4oz of water.
  24. S

    Why are B12 supplements making my symptoms so much worse?

    ...My brain is not working and I dont have any emotions at all. I just dont understand how B12 could cause more cognitive dysfunction, anhedonia, apathy and personality changes. I dont recognize myself at all. Methyl B12 made no difference. Can B12 lead to overmethylation, which could be...
  25. CSMLSM

    Why are B12 supplements making my symptoms so much worse?

    Hi, first I would like to say you have already been given some truly great advice by other members and it pleases me greatly that others are aware and sharing. I would like to add from my own experience and research with extreme B12 deficiency- CyanoB12 as mentioned inhibits the binding of the...
  26. S

    Why are B12 supplements making my symptoms so much worse?

    ...no control over what is happening. It is really scary. Could the B12 that I took have interfered with the withdrawal, and that made my anhedonia, apathy and cognition worse? As well as the restlessness? What should I do of the B12 is worsening my withdrawal-symptoms? Is it something to do...
  27. JES

    Why are B12 supplements making my symptoms so much worse?

    B12 can store in the liver unlike most other vitamins. Allegedly, the average person has enough B12 stores to make up for even three to five years after they stop consuming B12. Having said that, a three ounce serving of beef contains about 7 micrograms and average dietary intake is probably...
  28. Shanti1

    ME/CFS patient goes into remission after taking "elixir of youth" GDF11

    Thanks for reporting back, it's really valuable to hear your experience. I am going to continue to experiment with the GDF-11 and the frequency that works for me. I have to admit that when I don't use it too many days in a row, I feel shockingly better the day I inject it. I also use BPC-157...
  29. beatsmyth

    ME/CFS patient goes into remission after taking "elixir of youth" GDF11

    ...extremely powerful which has been the best supplement I have ever taken for all my CFS symptoms, has completely gotten rid of brain fog, anhedonia, tiredness, dullness, depression, etc. I am just wanting to make sure I can do a few months worth of runs with this on myself before sharing...
  30. S

    Why are B12 supplements making my symptoms so much worse?

    Do you know why the symptoms can last for up to eight weeks? Do you know the mechanism? Does B12 affect dopamine or serotonin? Since it drastically worsened my anhedonia? The anhedonia has been getting progressively worse since I took cyanocobalamin two weeks ago.