Search results for query: rs6323

...COMT V158M rs4680 GG -/- COMT H62H rs4633 CC -/- COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CC -/- VDR Taq rs731236 AA +/+ MAO-A R297R rs6323 GT +/- ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 AG +/- MTHFR 03 P39P rs2066470 GG -/- MTHFR A1298C rs1801131 GT +/- MTR A2756G rs1805087 AA...

...have been jumbled up with two SNPs within the coding region of the protein - viz the two SNPs which Lynch shows in his Strategene report - rs6323 and rs1137070 (items 15 and 19 resp) - and low and high activity promoters have been transformed into low and high activity enzymes (ie slow and...

...SOD2 (rs4880 ), GSTP1 (rs1695), NAT2 (rs1208) and NAT2 (rs 1801280) Heterozygoes - CYP1A2 (rs 762551), COMT (rs4633), COMT (rs4680), MAO-A (rs6323), CBS (rs 1801181 and rs234706), MTHFR (rs1801131 and rs2066470), MTR (rs1805087) MTRR (rs1801394) and SHMT1 (rs1979277) It seems like so many...

...COMT V158M rs4680 AG +/- COMT H62H rs4633 CT +/- COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CC -/- VDR Taq rs731236 AA +/+ MAO-A R297R rs6323 TT +/+ ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 AG +/- MTHFR 03 P39P rs2066470 GG -/- MTHFR A1298C rs1801131 TT -/- MTR A2756G rs1805087 AA...

...COMT V158M rs4680 AG +/- COMT H62H rs4633 CT +/- COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MAOA R297R rs6323 TT + MAOA rs2072743 T + MAOA T1011C rs1137070 C + MAOA T89113C rs2072743 C + MAOB rs1799836 C + MAOB A118723G rs1799836 C + ACAT102 rs3741049 GG...

Did you check your DAO status? Here is one article: http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2011.02548.x/full It does state that the genetic background of HIT is unknown. I don't think it even mentions my homozygous SNP, which is rs2111902, risk allele is G.

That SNP doesn't do anything. See here and here for posts on MAO A SNPs.

MAOA is involved in breaking down histamine so to some degree yes.

These aren't really involved in methylation. Yasko believes they're important in determining response to methyl units in supplements, but there's nothing to support that, and it's frequently contradicted by patient reports. As an example of Yasko's quackery, she reports a VDR SNP backwards...

...rs731236 AA +/+ (listed as -/- on Live Wello?) VDR Fok rs2228570 AA ff (Amy Yasko Methylation Pathway Analysis) MAO-A R297R rs6323 TT +/+ MTHFR C677T rs1801133 AG +/- MTHFR A1298C rs1801131 GT +/- MTR A2756G rs1805087 AG +/- MTRR A66G rs1801394 GG +/+ MTRR...

...me COMT V158M rs4680 AA +/+ COMT H62H rs4633 TT +/+ COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MAO-A R297R rs6323 TT +/+ ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 AG +/- MTHFR 03 P39P rs2066470 GG -/- MTHFR A1298C rs1801131 GT +/- MTR A2756G rs1805087 AA...

None of them have been shown to be significant. rs6323 aka R297R, in combination with several other SNPs, has been considered to be a proxy for a serious repeat polymorphism which does have significance, but the SNP alone doesn't do this. Here and here are posts which explains more about MAO A...

...COMT V158M rs4680 AA +/+ COMT H62H rs4633 TT +/+ COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MAO-A R297R rs6323 GG -/- ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 GG -/- MTHFR 03 P39P rs2066470 GG -/- MTHFR A1298C rs1801131 TT -/- MTR A2756G rs1805087 AG...

...COMT V158M rs4680 AG +/- COMT H62H rs4633 CT +/- COMT P199P rs769224 GG -/- VDR Bsm rs1544410 CC -/- VDR Taq rs731236 AA +/+ MAO A R297R rs6323 G -/- ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 AG +/- MTHFR 03 P39P rs2066470 AG +/- MTHFR A1298C rs1801131 GT +/- MTR A2756G rs1805087 AA...

...CFS. COMT V158M rs4680 AA +/+ COMT H62H rs4633 TT +/+ COMT P199P rs769224 AG +/- VDR Bsm rs1544410 CC -/- VDR Taq rs731236 AA +/+ MAO A R297R rs6323 T +/+ ACAT1-02 rs3741049 GG -/- MTHFR C677T rs1801133 AG +/- MTHFR 03 P39P rs2066470 GG -/- MTHFR A1298C rs1801131 TT -/- MTR A2756G rs1805087...

...161. Much too high for a woman. I am hetero MTHFR 1298...but what may be more telling in all this: COMT rs6269 GG ++ MTRR ++ and +- MOA-A rs6323 ++ MOA-B rs1799836 ++ plus two +-. Sadly, the supps I've been on for several months haven't done a thing---includes 400 mcg l-folate, the...

...A AG +/- CBS C699T rs234706 A AG +/- COMT rs6269 G AG +/- COMT H62H rs4633 T CT +/- COMT V158M rs4680 A AG +/- DAO rs3741775 C AC +/- MAOA rs6323 G GT +/- MTHFR A1298C rs1801131 G GT +/- MTHFR rs1476413 T CT +/- MTHFR rs4846049 T GT +/- MTRR A664A rs1802059 A AG +/- NOS2 rs2248814 A AG +/-...

Tricky question as in theory your faulty MAOA fails to break down both dopamine and serotonin. You could have plenty of both. Colonic motility is governed by the balance between the two though. So I would say: yes, try 5-htp for a bit. See how you feel and decide based on results. However, my...

...is over my head! This thread was mentioning 5HTP and I thought maybe that could help if I was indeed low on serotonin. But I do see that rs6323 is TT for me which you say means I'm downregulated. So, I need serotonin or no? I don't know the significance of most of the results of my...

...profile picture then "Browse raw data". In "gene" you can type MAOA or MAOB. Then you'll have to look at the various snp's. One of them is rs6323 You will have to compare your results to that of the general population yourself. This can be done by putting your all raw data into something...

Thank you for your replies. MAO-A R297R is at rs6323 and is TT. As for my personal level of aggressiveness, I have a pretty long fuse but there is a line that most people don't know exists until they cross it. Then they wish they hadn't. Not a physically violent person, but definitely not...

...the 2R promoter polymorphism is not enough to cause the problem. I suppose it's not as bad as all the internet chatter which claims that rs6323 IS the warrior gene and means that you have a slow form of the enzyme. Wrong on all counts. There are a few serious MAO A variants but R297R is not...

Hi Leo, You're certainly getting off on the right foot by getting both 23&Me and the OAT. I had my 23&Me done years ago and am just now doing the OAT tests... In any event I want to give you a quick summation of your SNP's and I'm by no means an expert, but I'm sure this will help get you...

...Now my genetic results from the Yasko website were : RS4680 COMT V158M +/- RS4633 COMT H62H +/- RS731236 VDR Taq TT RS2228570 VDR Fok ff RS6323 MAO A R297R +/+ RS1801133 MTHFR C677T +/- RS1805087 MTR A2756G +/+ RS567754 BHMT 2 +/+ RS651852 BHMT 8 +/- RS234706 CBS C699T +/- RS1801181...

VDR Bsm rs1544410 TT +/+ MAO-A R297R rs6323 TT +/+ MTHFR 03 P39P rs2066470 AG +/- MTHFR A1298C rs1801131 GG +/+ BHMT-02 rs567754 CT +/- BHMT-08 rs651852 TT +/+ I dealing with severe fatigue that seems to only be getting worse. As well my anxiety/ depression is getting much worse. If anyone...

...and surprisingly they were in the normal range. Here's my methylation /detox SNP's: rs1695 GSTP1 +/+ rs1208 NAT2 +/+ rs1801280 NAT2 -/+ rs6323 MAO-a + rs651852 BHMT08 +/+ rs1801181 CBS -/+ rs234706 CBS -/+ rs1801133 MTHFR +/+ rs1805087 MTR -/+ rs1801394 MTRR +/+ rs154410 VDR -/+ rs731236...

...the normal range , 7.6 if i recall correctly. Here's my methylation /detox genes: rs1695 GSTP1 +/+ rs1208 NAT2 +/+ rs1801280 NAT2 -/+ rs6323 MAO-a + rs651852 BHMT08 +/+ rs1801181 CBS -/+ rs234706 CBS -/+ rs1801133 MTHFR +/+ rs1805087 MTR -/+ rs1801394 MTRR +/+ rs154410 VDR -/+...

...Just having this promoter variation was not enough to cause problems. Please note this promoter polymorphism does NOT correlate with rs6323 (MAOA R297R) as is often erroneously claimed, nor does this SNP result in a slower or faster enzyme. Actually the SNP does nothing - the product of the...

...Will hydroxocobalamin be good for me; will it cause agitation in me? Gene SNPs COMT V158M rs4680 AA +/+ COMT H62H rs4633 TT +/+ MAO A R297R rs6323 T +/+ MTHFR C677T rs1801133 AA +/+ VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MTRR K350A rs162036 AG +/- MTRR A664A rs1802059 AG +/-...

Yeah, the homo A1298C definitely means you need supplementation with methyl supplements. Like another poster said, you should consider adding methyl folate if you haven't already. Dan Purser has a pretty good book on methylation called the 85% Solution, which you can get on kindle from...