Search results for query: MTHFR

Read the thing several times and then we can discuss it and get it clear. Sounds like you are having really bearable refeeding syndrome...

...a spasm in the abdominal muscles. The tests are the most important (from what I managed to pass during these 2 years): 1. Homozygous mutation MTHFR A1298C(Glu429Ala) C/C 2. Homozygous mutation MTRR gene: Ile22Met (A66G), MET/MET 3. Homocysteine - 7.4 4. Folic acid above the maximum...

I have the opposite problem it seems. My skin doesn't heal and nails don't grow if I don't take folate, but taking folate revs me up too much and gives anxiety. I just started taking glycine so hopefully that helps. I'm getting about 5g now. Hope that's enough.

Glad you found out about this issue from a simple saliva test! BTW The enzyme is referred to a COMT! Pam

...than the regular population. They should be standard screening in all moderately affected patients. I had to ask my doctors to give me the MTHFR test, after I self diagnosed myself with it. I am homozygous MTHFR. I didn't know about the COMPT thing. I wish there was an easy cheap test for...

Have you got feeling naturally sleepy????? When you were overmethylated, did you feel sleepy at all????

...things this is the first time some of my symptoms changed / disappeared. So I think I am open the right track somehow. I always suspected a MTHFR-Mutation that was responsible for most of my symtoms. My problem right now is: I am loosing too much weight since I am taking B12 and Folate. I...

With the SHMT1 mutation, should one avoid folic acid and vegetable folate like one with MTHFR mutations does? It looks like it's the step just before MTHFR. And should one supplement glycine as well?

Have you figured this out? Or, does anyone else know this? I've been using Hydroxocobalamin and folinic acid due to my COMT mutations, and recently added 1 cap Seeking Health Multivitamin Sensitive, but my results have not been consistent. My MMA is a little lower with this combination, but...

I'm not sure how you know where to draw the line between what is affected by nutrition and what is not? How do you know if a dysfunction has nothing to do with nutritional levels? I see the body as one fantastic system, all interconnected, with so much we have no notion of at all. What I do know...

...too many days in a row and had a methyl trapping situation... but im thinking if i spread out dosing it might be good. i am slow COMT and homo MTHFR c677t. The only b vitamin that is showing to be low for me is folate, but I figured I should take all of the bs instead of just the folate. now...

A person gets methylation started with MeCbl and methylfolate. You take more methylfolate to cure the folate deficiency symptoms that indicate more methylfolate needed. Then the symptoms change to the potassium deficiency symptoms. If you do not increase your potassium so it comes out right it...

...think thats just because of a lack of methylfolate? i'm wondering if I should take more folate bc the potassium hasn't worked on its own. is this something that is related to the slow comt or the mthfr or would happen to anyone with low folate? It's so interesting! Appreciate the help so much!

...to look for a hydro/adeno blend because of the slow COMT before seeing your posts in other threads! Along with slow COMT, I'm Homozygous C677t MTHFR, but most of my levels are fine except cellular folate is low. I did have very high mercury levels that I was detoxing, so Richard's point...

...have been researching Methylation since about 2017...experimenting with methylated vitamins, etc...I have subscribed to Livewello, Nutrahacker, MTHFR.net, Seeking Health Strategene, and a few others...I think I have a decent understanding about what my snps are and how they are possibly...

Thanks again. We can consider taking Niacin to break down too much of methyls. Regarding activation of COMT, someone gave me the following reply / tips. I thought I would share it here as well, maybe it helps someone. I am definately gonna try BCAA and eliminate foods that inhibit COMT.

...precious energy trying to figure stuff out. Maybe try the niacin. and hopefully if you start to feel better you can look into COMT gene and MTHFR but to be honestly it's a risky thing to start playing with bvitamins without an experts help - I personally woudl try and see this out with rest...

...1mg and have found it’s helped with emotional lability but not PEM. however emotional lability is part of ME due to our issues with our genes it’s all linked! https://ndnr.com/pediatrics/move-over-mthfr/ https://www.seekinghealth.com/collections/dirty-genes-comt-slow-support hope that helps

Apologies, I wasn't clearly. I have 2 heterozygous (yellow) mutations on MTHFR. MTHFR C677T: +/- heterozygous mutation MTHFR A1298C: +/- heterozygous mutation And COMT met/met (+/+). So I am in the same situation as you, MTHFR wants methyl but COMT doesn't. But I have no choice...

Hi @jason30 just to be clear, everyone has COMT and MTHFR, it depends what alleles you have and whether you are Hetero or homo for them to determine how your body may or may not respond to bvits. So if you are COMT met/met (slow to breakdown catechols) you may struggle with methyl folate and...

...I wonder what could be the cause? A search shows that people with COMT have issues with converting folinic acid. I do have COMT, as well as MTHFR. But how can I be sure if this is the case? Since my sleep gets better I believe I do convert it? Maybe it's a detox reaction. Does somebody have...

are you also COMT met/met? if so that can make it hard for you to tolerate mehtyl supps. Kind of puts us in a pickle if we are COMT met/met and have MTHFR (i'm hetero for the C677 and just gave up trying to improve my folate status through vitamins) and found more improvement supporting the COMT.

...doesn't answer your questions. Hopefully, someone else will come along soon and know something more. Anyway, here's one search page. Hopefully there also be a post or two that answers some of what you mentioned. https://forums.phoenixrising.me/search/647948/?q=MTHFR&o=date Welcome to PR. :)

Hi! I have a single MTHFR mutation (SNP rs1801133 A/G; rs1801131 T/T), folate levels: 2.7 low↓ (range 3-17), active B12 normal 77 (range 25-165). I've been on a very restricted diet for over a year due to vitamin A overload in the past, and react badly to vitamin A and carotene-rich foods. My...

...Kefir, I have a bad reaction to it. I become very fatigued, bloated, and mentally foggy. Because of my super-charged immune system (thank you MTHFR), it kicks me into a bad state. I stop, and a couple of days later I'm ok. Kefir is bacteria and my immune system sees it as an attack. Someday...

...after exposure of toxins or pesticides, or everything which is processed by the methylation pad. So there is the biggest problem (also MTHFR). When I am exposed I get huge inflammation in the body, as well as a huge fight/flight response. Also mast cells gets released (MCAS) and histamine...

It's been a long time... but are you still around? I've had almost identical experience as you.

see if it can help you: https://mthfr.net/preventing-methylfolate-side-effects/2014/11/26/

...which renders MTHFD1 non functioning and I think this is common amongst a European community. If it is combined with other mutations in MTHFR (from memor)y I think it can be more of an issue. I am heterozygous for MTHFR 1298C and when I did a 24 hour urine test for female hormones a couple...

...so since I was a toddler, all these back issues are interconnected and depreciate your existance, and I guess- Oh Well better luck next time. Thats about all I've got, is better luck next time. And I'm lucky it wasn't worse. And yes I have MTHFR and "mild" scoliosis on top of the larger list.