Search results for query: Noopept

  1. Hip

    Clonazepam (Klonopin) stops my symptoms almost completely

    ...and sometimes also depressed. But I do not get this issue with racetams, such as piracetam, which I take sometimes to counter brain fog. (Some racetams are also stimulants as well, but I avoid these). If I remember rightly, with noopept, it is advised to take breaks from this sometimes.
  2. Hip

    Clonazepam (Klonopin) stops my symptoms almost completely

    Noopept is a peptide analog of the active fragment of the antidiuretic hormone vasopressin. I =Hip&o=date']posted a few posts on it.
  3. Hip

    Clonazepam (Klonopin) stops my symptoms almost completely

    Desmopressin is one to look into for frequent urination. Also the racetam-like nootropic supplement noopept can help.
  4. Hip

    I'm 100% better, can function again

    I have tried quite a few racetams, but I always go back to the original and in my experience the best racetam: piracetam. I don't use it much though because ever since developing ME/CFS, I found that piracetam causes an emotion-flattening side effect. But if I need to focus on a complex task...
  5. Hip

    Hyperbaric without extra oxygen

    I've tried both of those (and quite a few other nootropics to boot), but noopept did not work any better than good old piracetam; plus noopept seems to cause depression withdrawal symptoms in me, and it's not recommended for long term use. NSI-189 did not do much for me, except reduce the...
  6. Hip

    Could high TNF-alpha be causing my symptoms? // Could Humira help?

    If anyone wants to try some TNF-alpha inhibitors (other than the standard ones like etanercept, which is expensive and has a black box warning regarding serious side effects), the following all have potent TNF-alpha inhibiting effects in vivo: An article on the use of etanercept in ME/CFS is...
  7. Hip

    Theoretical and practical treatments for neurogenesis? (Dr Hyde / HFME / Ramsay-ME)

    ...neurogenesis. The main neurotrophic factors that stimulate neurogenesis are BDNF, NGF and GDNF, and various supplements can stimulate these: noopept increases NGF and BDNF, idebenone promotes NGF, rehmannia glutinosa boosts GDNF, ibogaine increases GDNF, and the supplement...
  8. Hip

    Chronic Microglial Activation in ME/CFS, And Its Possible Treatment Using Microglial Inhibitors

    ...potent inhibitor of TNF-alpha production 1 Vinpocetine — potently inhibits TNF-alpha. 1 Taurine — significantly reduces TNF-alpha 1 Noopept — reduces TNF-alpha by half. 1 Wellbutrin (bupropion) — inhibits TNF-alpha, IL-1beta and gamma interferon. 1 Etanercept (Enbrel) — blocks the effects...
  9. Hip

    Completely eliminated my severe anxiety symptoms with three supplements!

    ...growth: Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain The nootropic supplement noopept increases NGF and BDNF in rat hippocampus, so this might be useful. Doses are around 25 mg of powder, taken sublingually. The supplement 7,8-DHF...
  10. Hip

    Coffee Enemas!!

    I only use noopept for short periods, usually a few days to a week. I take 30 mg sublingually or intranasally, always with 500 mg of oral choline bitartrate, as I read noopept alone can give you a headache. I find it has a mood boost as well as a cognitive boost, but there can also be a...
  11. Hip

    Coffee Enemas!!

    ...is unpleasant, as anhedonia is a horrible state of mind. For that reason, I rarely take these supplements. The only one that is OK for me is noopept; this gives me a bit of cognitive boost, but without the anhedonia payback. I used to take these acetylcholine stacks even before I had...
  12. Hip

    I'm 100% better, can function again

    By the way, bad news for those like myself in the UK: The incredibly badly thought out and clumsy Psychoactive Substances Act 2016, which basically bans everything that affects the mind (except alcohol, caffeine, nicotine, and drugs like antidepressants), may also ban nootropic drugs ("smart...
  13. Hip

    I'm 100% better, can function again

    ...its cognitive and motivational benefits seem to last well into the next day. Whereas I find piracetam wears off after half a day or so, and I find aniracetam wears off after just 2 or 3 hours. Noopept 30 mg tends to work best for me, though technically this is not a drug of the racetam class.
  14. Hip

    I'm 100% better, can function again

    ...long have you been taking this combination of drugs? I have tried a number of racetams, including piracetam, aniracetam, coluracetam, and noopept (though noopept is not technically a racetam). I find they help a lot with brain fog, but I find some racetams have side effects that make...
  15. Hip

    How to best gauge levels of brain fog & fatigue

    I was snorting 30 mg of noopept powder once a day, I think the effect lasted the whole day. I read that if you take noopept with say 500 mg of choline bitartrate, it prevents headaches appearing, so this is what I did. I found noopept also had an antidepressant effect, and I have some...
  16. Hip

    How to best gauge levels of brain fog & fatigue

    ...feeling, so it was not useful. Have you ever tried the nootropic drugs / supplements piracetam (or aniracetam which is very similar), and noopept? I find these help a lot for mental focus. Noopept is particularly good, and you only need a dose of around 30 mg of noopept powder (best taken...
  17. Hip

    Racetams/noopept ^acetylcholine and ^vasopressin ADH

    Yes, I read that noopept is usually grouped with the racetams, and has similar effects, but noopept is a peptide derivative of piracetam, so is not technically a racetam. Did you ever try fasoracetam (aka: NS-105 or LAM-105)? This is a racetam nootropic with antidepressant, anti-anxiety...
  18. Hip

    Racetams/noopept ^acetylcholine and ^vasopressin ADH

    Interesting observations, heapsreal. What dosing of noopept are you taking to get this reduction in urinary frequency? Noopept is a peptide analog of the active fragment of the antidiuretic hormone vasopressin, so this likely explains why it can reduce urinary frequency.
  19. Hip

    Unexpected benefits of piracetam - helps with muscle aches, improves physical function

    ...(which I have in addition to ME/CFS), and I try to avoid at all costs worsening these symptoms, because they are really awful symptoms. Noopept does not improve my brain fog as much as piracetam, but also it does not worsen the anhedonia and blunted affect, so now I will take noopept rather...
  20. Hip

    Unexpected benefits of piracetam - helps with muscle aches, improves physical function

    ...aniracetam. I find aniracetam works in a similar way to piracetam. I got great results in terms of combating brain fog from the smart drug noopept, when I took 50 mg intranasally each day (noopept is taken in low milligram doses). Strictly speaking, noopept not actually from the racetam...
  21. Hip

    Depression Poll

    ...daily) I find useful for both my anhedonia and depression in general. I got very fast acting antidepressant effects from the nootropic drug noopept, when I took 50 mg intranasally each day. Noopept also helps with the frequent urination symptom that ME/CFS patients can get (noopept is a...