Search results for query: molecular mimicry

This treatment method sent 93% of autoimmune diseases into remission

Even if you don t feel that if your reacting,it still causes inflammation,leaky gut and molecular mimicry ....plus glyphosate If not organic. In countries like Greece,France etc they also use a 48 hour fermenting process for their bread which lowers antinutrients and gluten a lot.i don t think...

...diagnosis in this subgroup of patients. When a bioinformatic analysis was performed on these epitopes, it revealed a potential molecular mimicry with several human proteins. To confirm these promising findings, a follow-up study will be conducted in a separate cohort of patients. The study...

...• Therefore, triggering chronic inflammation can contribute to autoimmune disease. • Post-Covid-19 autoimmunity may be due to molecular mimicry, bystander activation of T cells, transient immunosuppression, and pro-inflammatory cytokines, which might complicate SARS-CoV-2 vaccination...

...Is it possible that having elevated anti-phosphatidylserine or other antiphospholipid antibodies could perhaps be due to the molecular mimicry form of autoimmunity? For example, there are studies demonstrating how a persistent SARS-CoV-2 or Enterovirus can spread via extracellular vesicles...

Well, let's take a look at the different models of the development of autoimmunity: Molecular mimicry, where an immune response generated against a pathogen happens to cross-react against normal human tissue. This model is applicable to both B and T cells. Epitope spreading, where immune cells...

...2015) https://forums.phoenixrising.me/threads/epstein-barr-virus-genetic-variants-are-associated-with-multiple-sclerosis.36790/ Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk (Tengvall et al., 2019)...

...B Cells in Multiple Sclerosis Bind EBV EBNA1 and GlialCAM (Lanz et al., 2022) https://forums.phoenixrising.me/threads/study-clonally-expanded-b-cells-in-multiple-sclerosis-bind-ebv-ebna1-and-glialcam-2022.86795/ Main point: It presents an interesting hypothesis regarding molecular mimicry:

Thanks for posting this (Lanz et al., 2022) paper! It presents an interesting hypothesis regarding molecular mimicry: More on molecular mimicry: https://forums.phoenixrising.me/threads/how-viruses-cause-autoimmunity.86598/

https://www.nature.com/articles/s41586-022-04432-7 Having some difficulty extracting the abstract to paste it in. If someone else is able to that would be great. Another fascinating article about multiple sclerosis and EBV. Makes me wonder what equivalent studies could be done for ME if the...

...of the drug patent. Re-framing the Theory of Autoimmunity in the Era of the Microbiome: Persistent Pathogens, Autoantibodies, and Molecular Mimicry (Proal and Marshall, 2018) https://forums.phoenixrising.me/threads/why-autoimmunity-probably-doesnt-exist.75795/ Excerpt: (bolding added for...

Another good paper, which notes that perhaps too much emphasis has been placed on "genetic influences" when discussing the causes of autoimmunity: Virus infection, antiviral immunity, and autoimmunity (Getts et al., 2013)...

...studies suggest that the disease process in multiple sclerosis begins many years before any autoimmunity might be detected.) Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease (Fujinami et al., 2006) https://doi.org/10.1128/CMR.19.1.80-94.2006...

...Miller, 2009) https://forums.phoenixrising.me/threads/the-role-of-infections-in-autoimmune-disease.31721/ A paper that describes molecular mimicry and epitope spreading, as well as bystander activation and cryptic antigens. MOLECULAR MIMICRY and EPITOPE SPREADING: BYSTANDER ACTIVATION...

I am thinking molecular mimicry technology would be helpful with determining possible autoantibodies, and maybe there already is info out there relative to a1-aR and b2/aR. Along that line I found this paper. Molecular mimicry theory (MMT) suggests that epitope mimicry between pathogens and...

...EV and S1 similarly infect endothelial cells. Where is infection+inflammation there are AAB. This is why there is the end of the former sentence about molecular mimicry. To be clear: that's my statement, not Dr. Jaeger's. I just wanted to check if Dr. Pretorius knows about it. She does obviously.

would that help inform Davis and team of a particular avenue or flavour of drug to try via the Nanoneedle ? presumably not applicable to the yeast version of the tests (where nanoneedle has CFS blood)

...produce inflammation (epithelial inflammation that damages the cells). Furthermore, the pathogens produce proteins that due to molecular mimicry let the body produce AAB. The big??? is what is P.E.M. Is it low ATP (bc of hypoxia) being used up or do we have to think along the inflammatory...

...(EBV Exploiting the Immune System. Nature, Oct 2001) EBV can be a driver of Autoimmunity though activation of cytokine pathways and molecular mimicry (https://pubmed.ncbi.nlm.nih.gov/33613559/, https://www.frontiersin.org/articles/10.3389/fimmu.2020.587380/full) Critically ill COVID-19...

Thanks for that. Intuitively sounds right

...mitochondria (TCA cycle). -->Metabolic output of the infected cell is changed - The root cause of autoantibody generation is due to molecular mimicry -->proteins expressed by pathogens which are similar to human proteins Then she kind of sums up: All those different triggers (pathogens...

...about the potential B cell involvement in the autoimmunity in the article. btw, these 2 "theoretical" types of autoimmunity are molecular mimicry and epitope spreading. This is a good article that covers some interesting stuff on the topic. Oldie but goodie -...

...autoimmune disease: Re-framing the Theory of Autoimmunity in the Era of the Microbiome: Persistent Pathogens, Autoantibodies, and Molecular Mimicry (Proal and Marshall, 2018) https://forums.phoenixrising.me/threads/why-autoimmunity-probably-doesnt-exist.75795/ Excerpt: (bolding added for...

Related discussion: Re-framing the Theory of Autoimmunity in the Era of the Microbiome: Persistent Pathogens, Autoantibodies, and Molecular Mimicry (Proal and Marshall, 2018) https://forums.phoenixrising.me/threads/why-autoimmunity-probably-doesnt-exist.75795/ Excerpt: (bolding added for...

...Miller, 2009) https://forums.phoenixrising.me/threads/the-role-of-infections-in-autoimmune-disease.31721/ A paper that describes molecular mimicry and epitope spreading, as well as bystander activation and cryptic antigens. MOLECULAR MIMICRY and EPITOPE SPREADING: BYSTANDER ACTIVATION...

...cells conceal the PS on its inside surface. (This is the fundamental principle behind some antiviral strategies.) I doubt that "molecular mimicry" would be involved here- I think that "epitope spreading" might be a more applicable explanation for the emergence of auto-antibodies. EDIT: For...

I'm not sure I follow. You're saying PS antibodies might be increased due to an increase in damaged cells? I know they've found PS antibodies more in long covid and ME/CFS than in healthy people. Though, it's like 5% compared to 1%. I just see molecular mimicry.. though maybe i'm over simplifying.

A rather good article. It mentions three ways that viruses can cause autoimmunity: Molecular mimicry, where an immune response generated against a pathogen happens to cross-react against normal human tissue. Epitope spreading, where immune cells mistake human tissue that is near a pathogen as...

...less cell wall strength. Autoimmunity is often or maybe even always from lack of cell wall integrity in the gut (eds) creating molecular mimicry, then autoimmunity. Trust me, I don't want eds to be true, cos then we are looking at CRISPR and stem cells. Of course we may be able to treat...