Search results for query: metabolic

Professor Thomas Seyfried recommends keto diet + 20% caloric restriction to starve cancer cells by taking advantage of 'Warburg effect'. (55mins) I prefer the below video to the one above. One of the most interesting interviews I've listened to this year. :thumbsup: (99mins) The Hard Facts...

Multi-omics provide evidence for an anti-inflammatory immune signature and metabolic alterations in patients with Long COVID Syndrome; an exploratory study Abstract Despite the increasing prevalence of patients with Long Covid Syndrome (LCS), to date the pathophysiology of the disease is still...

Pre-Illness Data reveals Differences in Multiple Metabolites and Metabolic Pathways in Those Who Do and Do Not Recover from Infectious Jason et al, 2022 Abstract Metabolic pathways related to energy production, amino acids, nucleotides, nitrogen, lipids, and neurotransmitters in myalgic...

Fibroblast growth factor-21 as a novel metabolic factor for regulating thrombotic homeostasis Shuai Li, Haibo Jia, Zhihang Liu, Nan Wang, Xiaochen Guo, Muhua Cao, Fang Fang, Jiarui Yang, Junyan Li, Qi He, Rui Guo, Teng Zhang, Kai Kang, Zongbao Wang, Shijie Liu, Yukai Cao, Xinghao Jiang, Guiping...

https://pubmed.ncbi.nlm.nih.gov/28509906/

Cardiopulmonary, metabolic, and perceptual responses during exercise in ME/CFS: A Multi-site Clinical Assessment of ME/CFS sub-study (Cook et al., 2022) https://doi.org/10.1371/journal.pone.0265315 A study that provides more evidence of exercise intolerance in ME, and evidence that this...

Hello, I'm wondering if I can test 5-HTP capsules without worsening the possible Metabolic Trap. If I understand it correctly, it is still unclear whether you have too much or too little serotonin as a result. My symptoms tend to feel like too little and a urine test (which I know has little...

https://www.sciencedaily.com/releases/2022/02/220210154147.htm "A recent study explains an essential component for proper mitochondrial function: The protein complexes MICOS and ATP synthase can communicate with each other." "Mitochondria, the power plants of the cell, make massive...

Authors: Achilles Ntranos, Hye-Jin Park, Maureen Wentling, Vladimir Tolstikov, Mario Amatruda, Benjamin Inbar, Seunghee Kim-Schulze, Carol Frazier, Judy Button, Michael A Kiebish, Fred Lublin, Keith Edwards, Patrizia Casaccia Published on: December 11, 2021 doi: 10.1093/brain/awab320 Abstract

“Straining for Energy”- Large Metabolic Study Suggests ME/CFS is an “Immunometabolic” Disease Now comes a big, complex, and undoubtedly quite expensive Norwegian metabolic study. In fact, one of the authors called the study “A map of metabolic phenotypes in patients with myalgic...

Hi guys, I hope everyone is doing as okay as possible. Here is the latest update from Prof. Ron Davis on the Metabolic trap hypothesis: Big thanks to Ashley Haugen for her hard work on this, and of course to Ron (and Janet). B

Chris Armstrong and the Hunt for the Metabolic Underpinnings of ME/CFS https://www.healthrising.org/blog/2021/10/17/chris-armstrong-chronic-fatigue-syndrome-metabolism/ Conclusion Chris Armstrong and the 5th Open Medicine Foundation-funded research center in Australia are on something of a...

Hi everyone, I had a Genova MAP test done a few years ago. I think it's now called an Organic test. I didn't get anyone to interpret it since it seemed to show all was in range except for B1 which was borderline. I read an article today about B1 deficiency and CFS and hecne thought I should go...

Groven N, Reitan SK, Fors EA, Guzey IC. Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. Psychoneuroendocrinology. 2021 Sep;131:105287. doi: 10.1016/j.psyneuen.2021.105287. Epub 2021 May 27. PMID: 34090138. Abstract

A map of metabolic phenotypes in patients with ME/CFS (Hoel et al., 2021) https://insight.jci.org/articles/view/149217 A new metabolomics paper from the Norwegian team of Øystein Fluge and Olav Mella. In addition to providing additional support for the finding that ME cells have impaired...

So in terms of the Metabolic Trap Theory. As i am severe now after taking a 5-HTP supplement (bravo, wanja, well done) and my brain doesnt work properly anymore. Did anybody know of someone or had the same experience after taking such a supplement? Would LDN or LDA help in this situation...

...I believe ME/CFS results when your body has chronic persistent infections that your immune system can no longer handle or kill, a metabolic trap being induced, along with brainstem and vagus nerve dysfunction contributing to it. A metabolic trap most likely gets induced when pathogens cause...

There is one thing in the IDO theory I can't figure out - the inconsistent piece that actually makes me suspect that there is something more complex going on. Here is the story, extending what I wrote in the original IDO post, if you aren't familiar with the Ron Davis research yet. As a...

ron davis said he hasn’t yet begun testing fda approved drugs on the yeast inflicted with the metabolic trap because the robots that will be aiding in the process are not yet fixed (he said this yesterday in a QNA). i’m curious if anyone knows how long the process of testing all fda...

Does anybody know if there are any possible ways B12 might make a patient feel better in Ron Davis's model of ME? I read about his metabolic trap theory, but can't even remember it, so if anybody can link to a good explanation, I'd appreciate it. Am I making this up or did Ron say something...

...2021 Apr 16;S1550-4131(21)00166-2. doi: 10.1016/j.cmet.2021.03.025. Online ahead of print. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine Deyang Yu 1 ...

...who also acquire the disorder (minus the menstrual dysfunction). Recently, the IOC has expanded the physiological impairments to include metabolic, immunity, cardiovascular, gastrointestinal, and haematological consequences. Source: BMJ content/52/11/687 Source: Wikipedia Source...

...Symptoms. Front. Neurosci. 12:499. doi: 10.3389/fnins.2018.00499 Abstract How is this relevant? One of the unsolved questions of the metabolic trap theory is why and how it happens and what mechanism(s) participate in the relapsing process. This study gives one possible explanation, i.e...

...exercise, this study is worth investigating for how it may apply to ME/CFS. What are we missing out on? And what does this say for those of us doing high intensity aerobic exercise prior to becoming ill...

...entire illness I've always felt that one of, if not the main issue for me has been problems with creating energy from food and some sort of metabolic disturbance or disorder. I say this because: 1. I get very frequent serious hypoglycemic attacks following physical exertion (despite not...

I still think the metabolic trap theory has some merit. Robert Phair looked into genetic problems and his current theory is that tryptophan metabolism gets overloaded and we don't have the ability to process it and so we get stuck in a trap. The enzyme which can process it is IDO1, as we lack...

...wanted a way to measure if I was over my AT but do not understand the tech on it and see if it would applied to CFS. https://www.lumen.me/metabolic-flexibility Lumen measures the C02 levels in your breath to interpret if your body is using carbs or fats for fuel. I do not have any...

...connect with these guys at Silicon Valley Exercise Analytics, that just published an article in Nature on the tradeoff between V02Max and metabolic efficiency. If the way athletes train is critical to their performance, I think we might learn a LOT more about the nuanced details of HOW the...

...and a dearth of mechanistic hypotheses regarding its etiology and possible cure. A new hypothesis, the indolamine-2,3-dioxygenase (IDO) metabolic trap, was developed and formulated as a mathematical model. The historical occurrence of ME/CFS outbreaks is a singular feature of the disease and...

...hypothesis Hello again, everyone. Welcome, to the RBC-NOX hypothesis, which I consider by far my best idea yet. It connects the IDO metabolic trap, red blood cell deformability, craniocervical instability (including recoveries after surgery), Alan Light’s research on fatigue signaling...