Search results for query: mitochondria

  1. B

    How the Krebs cycle powers life and death

    Really interesting simplifying presentation about the Krebs and energy cycle by the Royal Institute. Goes over the history of the finding for mitochondria and some of the simplified chemistry and variants of cycle.
  2. A

    Minczuk et al / Mitochondria research reported in Guardian 6.26.22

    https://www.theguardian.com/science/2022/jun/26/can-our-mitochondria-help-to-beat-long-covid
  3. M

    Is there a way to negate the negative mitochondrial effects of antivirals?

    I'm due to start Acyclovir and from researching it seems most antivirals cause some degree of Mitochondrial Toxicity. Is there a way to avoid or negate these toxicity side effects? From this table there's a host of effects from Acyclovir: Source...
  4. C

    Red/Infrared light therapy, no equipment

    ...by the sun. why? Sunlight is rich in red and infrared light preliminary research suggests these longer wavelengths of light support mitochondrial function and reduce oxidative stress. red and infrared light can penetrate glass, light clothing, skin and bones. It's benefits can spread...
  5. K

    Mitochondria efficiently adapt to changing metabolic conditions, published Feb 10/22

    https://www.sciencedaily.com/releases/2022/02/220210154147.htm "A recent study explains an essential component for proper mitochondrial function: The protein complexes MICOS and ATP synthase can communicate with each other." "Mitochondria, the power plants of the cell, make massive...
  6. L

    If CoQ10 improves symptoms, what else should also help?

    Does anyone have any advice that if CoQ10 improves symptoms, then what else might also work, given CoQ10's actions in the cell and ME pathophysiology? If I take 1400 mg ubiquinol it takes a couple of hours to start working, but it pretty consistently helps with some of the worst ME symptoms for...
  7. Pyrrhus

    A systematic review of mitochondrial abnormalities in ME/CFS/SEID (Holden et al., 2020)

    I thought this 2020 meta-analysis from Staines and Marshall-Gradisnik had already been posted, but I must have missed it... A systematic review of mitochondrial abnormalities in ME/CFS/SEID (Holden et al., 2020) https://dx.doi.org/10.1186%2Fs12967-020-02452-3 Excerpt:
  8. elvira

    KL1333 Mitochondria medicin

    The medicin KL1333 has been approved a phase 2 study. It’s for mitochondrial diseases that one is born with - but do you think it could benefit some people with ME/CFS too? 🤔...
  9. Hip

    Morten Group Oxford video details their research: the cause of PEM, mitochondria, leaky gut, L-form bacteria, Raman spectroscopy, etc

    ...ME/CFS research. The Morten Group are doing lots of interesting ME/CFS work: Mechanisms behind PEM Factors in the blood that influence mitochondrial function Bacterial toxins The role of microbes in the gut in ME/CFS Intestinal hyperpermeability (leaky gut) in ME/CFS patients L-form...
  10. Hip

    In the brain, energy and ATP produced by the MYELIN SHEATH mainly, and not the mitochondria, study suggests!

    ...group focused on the role of bacteria in ME/CFS, among other things. At timecode 20:30 of the video, Dr Morten points out that the mitochondrial density in the brain is only 5%, whereas in other organs like the heart, kidney and liver, the mitochondria density is 20% to 40%. This is...
  11. W

    Artificial Mitochondria

    https://singularityhub.com/2021/09/21/scientists-created-artificial-mitochondria-that-can-make-energy-for-damaged-cells/ Early development, but if ME really does involve mitochondrial dysfunction, artificial boosting of ATP inside cells might be useful for research. The technique for directing...
  12. Pyrrhus

    Role of mitochondria, oxidative stress & the response to antioxidants in ME/CFS: A possible approach to SARS-CoV-2 ‘long-haulers’? (Wood et al., 2021)

    From the team of Warren Tate who, I am obligated to say, comes from New Zealand: Role of mitochondria, oxidative stress & the response to antioxidants in ME/CFS: A possible approach to SARS-CoV-2 ‘long-haulers’? (Wood et al., 2021)...
  13. A

    Could D-Lactate be the source of Toxic Brain Cells and damage to Mitochondria resulting in Dysfunction and Fragmentation?

    ...factors in ME/CFS blood that can cause mito dysfunction..." GoFundMe Could D-Lactate be the source of Toxic Brain Cells and damage to Mitochondria resulting in Dysfunction and Fragmentation? D-Lactic acid enters every cell and affects every organ including the Brain? D-Lactate and other...
  14. Pyrrhus

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS (Maksoud et al., 2021)

    Another literature review from Staines and Marshall-Gradisnik: A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS (Maksoud et al., 2021) https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4 Excerpt:
  15. W

    Proline Inhibits Mitochondria

    ...provide an insight into the core dysfunction of ME and/ or PEM. Why might proline be involved in ME? Well, proline is critical for mitochondrial function. This paper explains it: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752965/ "Proline dehydrogenase (PRODH), a.k.a. proline oxidase...
  16. ChookityPop

    PUFAS/Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease?

    ...of talk out there about how bad polyunsaturated fats like seed and vegetable oils are and I just thought I should share this podcast with you guys. How Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease, with Tucker Goodrich Eating seed oils is about as smart as eating...
  17. junkcrap50

    Two Molecules (SS-31 & NMN) Targeting Mitochondria Synergistically Improve Aged Heart Function

    Article: https://www.nmn.com/news/two-molecules-improve-heart-function Journal Paper: https://pubmed.ncbi.nlm.nih.gov/32779818/
  18. godlovesatrier

    Covid-19 effect on mitochondria and hhv6 interaction (Bhupesh Prusty)

    I've just seen this tweet from Bhupesh. Excited to see the results. Would be interesting to see how covid19 behaves for the long hauler/MECFS overlap.
  19. sometexan84

    Cause of EBV Fatigue found + Biomarkers (Mitochondria “Cellular Chronic Fatigue")

    ...below the links, along w/ an email response from those that made the discovery. An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Cell-Based Blood Biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome As...
  20. mitoMAN

    Promising Mitochondrial Peptides: SS-31 / Elamipretide + MOTS-c and Humanin

    ...name SS-31 (licensed name will be elamipretide) This peptide seems to have grabbed the attention of scientists researching a healing for mitochondrial myopathies. Ron Davis mentioned this as one possibly working peptide to help CFS patients! Randomized dose-escalation trial of elamipretide...
  21. Learner1

    Mitochondria - Regulating SIRT1 - resveratrol, curcumin, quercetin, and EGCG

    I've found a lot of papers lately describing the very positive effects of these 4 substances. Curcumin, quercetin, resveratrol and EGCG are worth taking for a lot of reasons. https://www.academia.edu/8636596/Regulation_of_SIRT1_in_cellular_functions_Role_of_polyphenols They've all been great...
  22. W

    Nasal Cells and Mitochondria

    ...harm brain health, as the olfactory mucosa can act as a key pathway to the brain. I noticed this: "The researchers also identified the mitochondria-targeted NPTX1 gene, which has been shown previously to be associated with brain disorders, as a key driver of mitochondrial dysfunction upon...
  23. Jwarrior77

    ATP 360 supplement for the mitochondria?

    Anyone try this: https://www.researchednutritionals.com/product/atp-360/ The same doctor recommended it. Seems like a bunch of good ingredients to support mitochondria function.
  24. Annikki

    New research suggests genetic material from the mitochondria can trigger an immune response throughout the body

    I found this really interesting. This finding about mitochondria ties them to not only energy production, but to autoimmunity and inflammatory cytokines. My guess is relates also to PEM:
  25. Belbyr

    Muscle Mitochondria research in CFS

    I know many of you here keep up with the CFS research like I try to do. Has anyone heard any updates on the muscle biopsy studies that were talked about almost a year ago? I believe Dr Systrom was going to be heading this up. This was an interesting article on a CFS patient that did a muscle...
  26. Murph

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS patients 9/2019

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Daniel Missailidis , Sarah Annesley , Claire Allan , Oana Sanislav , Brett Lidbury , Don Lewis , Paul Fisher * Version 1 : Received: 3 September 2019 / Approved: 4...
  27. W

    Mitochondria 'Shorting Out'

    https://phys.org/news/2019-08-tiny-thermometer-mitochondria-cell-unleashing.html The article is about a technique for measuring temperature in mitochondria, but the interesting thing from an ME perspective is the finding that mitochondria store energy in a 'proton battery' and this can get...
  28. A

    Ketogenic diet & mitochondria

    Asking everyones views , is ketogenic diet good for mitochondria function in general, better even than any so called normal diet which have more carbs ? I just semi-randomly read again about feeding mitochondrias, and this caught my eye : "One of its leading advocates is neurologist Jong Rho...