musicchick581
Senior Member
- Messages
- 115
What has been debunked from Amy Yasko's research? I'd like to know what is accurate and what is not. If there are threads on here about it, can you post the threads?
-
Welcome to Phoenix Rising!
Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
To become a member, simply click the Register button at the top right.
Yasko-what has been debunked?
- Thread starter musicchick581
- Start date
Her CBS theories are based on badly misreading research. The SNPs just have a minor impact. It is possible that sulfur problems are arising through a different mechanism, or that the gene is upregulated by external factors, but the SNPs themselves are mostly irrelevant. The treatment suggested by her for CBS might have an impact, but the basis of her justification for that treatment is completely groundless.
The AHCY SNPs which Yasko focuses on also have little or no impact.
Anyhow, I looked up the research for almost all of them at some point, and started threads in the SNP subforum entitled "Interesting <gene name> Variations". So if you search for "Interesting MTHFR Variations" and "Interesting AHCY Variations" in that subforum, you'll find my lists of which 23andMe SNPs on those genes have an impact, and usually a brief discussion of research data which contradicts Yasko's conclusions. I haven't cited the research for most of those, but have lists of some of it on my laptop, and all of it can be found at google scholar or the research linked to the SNPs at http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs= . Snpedia.com is a good option if you want simpler but mostly accurate summaries.
At the end of the day, there's just too many inaccurate claims out there about SNPs to trust any of them. If you want to be certain, read the research yourself.
The AHCY SNPs which Yasko focuses on also have little or no impact.
Anyhow, I looked up the research for almost all of them at some point, and started threads in the SNP subforum entitled "Interesting <gene name> Variations". So if you search for "Interesting MTHFR Variations" and "Interesting AHCY Variations" in that subforum, you'll find my lists of which 23andMe SNPs on those genes have an impact, and usually a brief discussion of research data which contradicts Yasko's conclusions. I haven't cited the research for most of those, but have lists of some of it on my laptop, and all of it can be found at google scholar or the research linked to the SNPs at http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs= . Snpedia.com is a good option if you want simpler but mostly accurate summaries.
At the end of the day, there's just too many inaccurate claims out there about SNPs to trust any of them. If you want to be certain, read the research yourself.
musicchick581
Senior Member
- Messages
- 115
Thank you. I have an appointment out at Mensah Medical (specialists in MTHFR and methylation) and they studied with Dr. Walsh, a lead researcher. I posted here because I've done SO much research that it's overwhelming now and I don't want to go to the appointment with the wrong information and having wasted time trying things that are irrelevant. My sulfates in urine are high, eating slightly cooked yucca has helped me feel less stress after eating meat. I don't its impact on my urine sulfates. I'm not sure why they are high but the charts online show its the urea cycle.
I will check out your link and info. Thanks again!
I will check out your link and info. Thanks again!
ahmo
Senior Member
- Messages
- 4,805
- Location
- Northcoast NSW, Australia
@musicchick581 Yasko's CBS info has been invaluable for me. Sulfate strips were never above the 2nd level, within ok range. But I had ongoing negative reactions to sulfur/high thiol foods and supps. Using the appropriate ammonia-reducing aminoes has been a boon for me. I also got great support from Yasko's CBS RNA formula. I initially used this w/ each meal, now only twice a week as I've continued healing.
musicchick581
Senior Member
- Messages
- 115
Hmm...I wonder why the discrepancy?
ahmo
Senior Member
- Messages
- 4,805
- Location
- Northcoast NSW, Australia
From my reading here at pr and GAPS forums, CBS SNPs are problematic for many, and managing them helps many. Scientific literature hasn't been of any use to me in my healing journey. Anecdotal evidence and my own experiences have led me down a path of increasing wellness. In some aspects I'm managing things better, have far greater understandings of how to do that. In other respects, I'm quite clearly healing from long term leaky gut, "symptomless" celiac/gluten intolerance, B12/folate deficiencies, liflelong accumulations of metals.