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XMRV not found in peripheral blood cells from treatment-naive HIV+ patients

Jemal

Senior Member
Messages
1,031
I think this is a new negative study (says it was accepted 18 may).

The human pathogen xenotropic murine leukemia virus-related virus (XMRV) has been tentatively associated with prostate cancer and chronic fatigue syndrome. Unfortunately subsequent studies failed to identify the virus in various clinical settings. To determine whether XMRV circulates in humans and the relationship with its host, we searched the virus in 124 HIV infected patients who might have been exposed to XMRV, might be prone to infection due to progressive immune deficiency, and had not been treated with antiretroviral drugs yet. Using nested polymerase chain reaction (PCR) and single step TaqMan real-time PCR, both designed on XMRV gag gene, we could not find any positive samples. These findings add to the growing amount of skepticism on XMRV.

http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03580.x/abstract