I've lived with M.E for more than 30 years and throughout this time have tried many therapies and supplements etc with limited results. I'm posting here as I'm seeking some advice: My symptoms have always got substantially worse in the winter (for reference, I live in London, England). There's a point each autumn (which varies sometime between October & November) when as though a switch has been flicked I will wake up feeling heavy limbed and over- fatigued and that's it I know from then until next April/May I will be running on M.E time, everything will be a struggle. As I'm getting older this pattern is become more pronounced and like the characters in Game of Thrones I dread the onset of winter. I'm curious, do other people experience this and if so what do you do about it? Is it possible that in addition to M.E I'm experiencing S.A.D ? I've tried using daylight bulbs, 5htp, St. John's Wort, L theanine, exercise, and so on but the pattern remains the same. This winter I'm thinking about taking Prozac or similar. In the past I've always tended to avoid drugs like these but as I know the next 6 months are going to be hard work I'm open to anything. Your thoughts/ advice appreciated. Thanks.