Permission to repost Prof. G Canada: why I think MS is caused by a virus I now want to get the next phase of the Charcot Project off the ground ASAP "As promised my presentation that I gave at the grand round in London, Ontario. I got a lot of verbal support from attendees at the lecture for the Charcot Project. Their support makes me want to get our IM, EBV and HAART trials off the ground ASAP. As always we need funding." Xenforo plugin would not allow slideshare.net code so those who are interested click on the link below http://www.slideshare.net/gavingiovannoni/why-i-think-ms-is-an-infectious-disease-for-the-blog Also J Neuroimmunol. 2014 May 15;270(1-2):51-5. doi: 10.1016/j.jneuroim.2014.02.013. Epub 2014 Mar 6. Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis peptides are cross recognized by anti-myelin basic protein antibodies in multiple sclerosis patients. Mameli G1, Cossu D1, Cocco E2, Masala S1, Frau J2, Marrosu MG2, Sechi LA3. Author information Abstract Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis (MAP) have been associated to multiple sclerosis (MS). We searched for antibodies against the homologous peptides Epstein-Barr virus nuclear antigen 1 (EBNA1)400-413, MAP_0106c protein (MAP)121-132, and myelin basic protein (MBP)85-98 on a MS Sardinian cohort, showing that these antibodies are highly prevalent among MS patients compared to healthy controls. Competitive assay demonstrated that antibodies recognizing EBNA1400-413 and MAP121-132 cross-react with MBP85-98, possibly through a molecular mimicry mechanism. Indeed, the fact that peptides from different pathogens can be cross-recognized by antibodies targeting self-epitopes supports the hypothesis that EBV and MAP might trigger autoimmunity through a common target.