Things have dramatically changed for me over the last few weeks. I had to go to toothpick amounts of methylfolate and methyl b12 because my reaction to them was so over caffeinated and my body couldn't keep up with the healing it was bringing on. I felt so hyper that I was almost ready to give up. But then things calmed down. I am now up to quarter tablets of 1000 mcg's B 12 and 400 mcg's methylfolate. I have no doubt that I will soon be able to tolerate effective doses soon. I probably could tolerate them now but don't want to move up too quickly. I am increasing my dose every three days as long as I have no adverse side effects. But over the past few days I have been feeling incredibly lethargic in contrast to when I first started. Since methylation I take a no chocolate, no green tea, no co q10 because my energy is raging until a few days ago when the lethargy I used to have came back with a vengeance! Is it time to add l-carnitine fumarate? Can I just take plain l-carnitine? Is it too soon? How about CoQ10? Or perhaps I should rapidly increase my doses of B12 and methylfolate? Need something to get my mitochondria to work. I feel so incredibly tired and I have a midterm in a few days. Any suggestions would be appreciated!