I am severe cfs. Mostly housebound. I find on cipralex aka Lexapro at 20mg very toxic to me. I have tapered down to 10mg but still it makes me fatigued and makes my PEM much much worse. I need to switch ssri. Yes I realize I’d probably be better off not on antidepressants. With severe CF I have major depression being trapped on a couch 12 hrs a day and cannot cope with this illness otherwise. Anyone found a ssri they can tolerate with the least fatigue ?