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Vinpocetine For Brain Fog/Anxiety Might Not Be a Good Idea

Discussion in 'General Treatment' started by Lotus97, Feb 19, 2013.

  1. Lotus97

    Lotus97 Senior Member

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    I've been trying Vinpocetine for the past few days and I've experiencing inconsistent results. It seems to actually been making my brain fog worse. I'll post more later after I've been taking it for a few more days, but first I'm going to stop for a few days.

    Has anyone else had problems from taking Vinpocetine? I came across a thread on another site where other people were having similar experiences. There were also some questions raised about it's effect on dopamine, NMDA, and AMPA.
    http://www.longecity.org/forum/topic/23457-vinpocetine-ditch-it/
     
    Eiren likes this.
  2. Hip

    Hip Senior Member

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    I get good results from vinpocetine, and in fact I have taken 10 mg every day now for a long time. It makes my head a little clearer.

    I also find it increase emotional tone, and since I suffer from some anhedonia and emotional flatness symptoms, I like things that seem to ramp up a my brain's flat emotional circuitry. But it is only a mild boost in emotions. Though I have read that other people find vinpocetine lowers their emotions, and causes depression. So it seems like there is a varied response.

    One interesting thing about vinpocetine is that its bioavailability is only 7% on an empty stomach but 60-100% with food . Big difference.
     
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  3. ramakentesh

    ramakentesh Senior Member

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    While it is reputed to increase cerebral blood flow it may do so in ways that are counterintuiative in OI.
     
  4. Lotus97

    Lotus97 Senior Member

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    Vinpocetine increases acetylcholine which can be a good thing or a bad thing:
    http://forums.phoenixrising.me/inde...acetylcholine-toxicity-the-cause-of-cfs.9757/
    Vinpocetine does seem to have a lot of other benefits however. I wonder if it's not a good idea to take too many things that increase circulation because this says not to take with ginkgo or garlic (both of which increases circulation).
    http://www.wisegeek.com/what-is-vinpocetine.htm
     
  5. ramakentesh

    ramakentesh Senior Member

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    Doesn't it have nitric oxide effects?
     
  6. baccarat

    baccarat Senior Member

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    I don't know if it does but it lowers blood pressure.
     
  7. Eiren

    Eiren

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    Necro thread alert! :ninja:

    But I started taking Swanson Gingko with Vinpocetine a few weeks ago, first once a day, then upped to 3x a day (so 15mg Vinpo per day). Then I had a really bad crash. Like, not just exhausted (though at first I thought it was just another bout of exhaustion) but also dizzy, cotton-ball head brain fog, and totally apathetic and "flat."

    Sometime in the midst of laying in bed feeling too heavy to move last weekend I started having a little thought of "hmmm...maybe this could be a side effect of something?" The vinpo was the only new thing I was unfamiliar with, so I googled and didn't find much beyond the "increase blood flow, good for brain!" spiel I read back when I first decided to order it. Then I search PR and came across the above post and the linked discussion. And yes. Yes, I think it was the vinpo. I "liked" the first post that day, but didn't feel at all motivated to make this post until now.

    I didn't take the vinpo since then, and I'm starting to feel better. So yeah, this is definitely one supplement that can have a bad effect. Though I must say that I am sensitive to meds, and have a bad reaction to a great number of them. I also can't handle SSRI and got serotonin syndrome once from a low dose of them. The effect vinpo can have on serotonin/dopamine may have been behind my reaction.

    Basically, I'm going to go out on a limb and recommend that if you respond poorly to SSRI's or the like you should stay away from vinpocetine.
     
    Mary likes this.

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