I think my brain fog is at least somewhat caused by poor blood flow... I don't have POTS, but I'm starting to think that maybe I do have some subtle vascular problems that are causing big cognitive problems... I've ignored this part of CFS since I don't have POTS... Can anyone share info on "vascular dementia" or vascular brain fog? I took high doses of ornithine/arginine a few years ago and felt fantastic and super, super focused (unbelievably organized...and great burst of energy).. THEN I crashed hard.. one of the worst reactions... However, it did teach me that blood flow and inflammation were causing so bad symptoms... I'm trying arginine again BUT adding lysine this time... rookie mistake to leave the lysine out the first time around... No ornithine in the house, and I'm broke, so I'm working w what I have. do you really need ornithine w arginine and lysine? I know these 3 are often taken together, as well as those 3 plus glycine - which is also good for me but makes me sleepy.