Is there any reason for Tumeric or NAC to make you feel worse? I have felt so bad lately with my iron and ferritin levels low. Although, my CBC was normal. I'm now taking Hydroxy and Methylfolate. I was hoping that the addition of methylfolate would make me feel better. It hasn't. However, I added Tumeric and NAC a couple of days ago. Could either of those make it worse with MTHFR? Seems they both come highly recommended. Dr. Yasko says Tumeric is a methyl donor.