Hello everyone, I‘ve been a silent reader for a while and really appreciate all the shared knowledge and experiences in this place. I‘ve recently stumbled over Diana Driscoll and her (and others) theory that POTS may be a result of antibodies against the acetylcholine receptors. I have a really hard time understanding what is happening in a case like that, so I wanted to ask if someone could help me make understand. If there are antibodies against acetylcholine receptor does that mean the receptor for acetylcholine is blocked? And in the consequence is there too much or too low acetylcholine in the body? And what do anticholinerg medications do? Do they block the receptors, too? I only find explanations that they are working against acetylcholine... but not what that means, practically. Thanks a lot, this is all very hard to understand.