Hi, I have a strange problem! Each time when I need to focus, my adrenalin raise sky high, also it’s seen on my HRV meter. But my brainwaves are delta dominant at daytime (I have this checked by a neurofeedback therapist). This is a rare mix. It’s make me fatigue and it gives me an adrenalin rush at the same time. Nobody understands it! Now I did a 23andme test and I see a COMT and a MAO A and BHMT 2/8. What I think is that my dopamine remains too long in the synapse and is converted into adrenaline, is this possible?
My serotonin remains too long in the synapse and is converted into melatonin. Or is it something else?
I tried Methyl B12 and TMG but this makes my problem worse. I think I’m over methylated.
CBS: I’m not sensitive to sulfur.
Diet: paleo
I now use 1x Hydroxy B12 10.000ug
2x 400mcg Methylfolate
1x zinc 50mg
3 vit c 3000mg
1x vit d 5000
1x vit e 400
6x magnesium 200mg
2x molybdenum 100
What to do about the adrenalin and delta dominance?
ACAT1 rs3741049 A AG +/-
ACE Del16 rs4343 G AG +/-
AGT M235T/C4072T rs699 A AG +/-
AHCY-01 rs819147 C TT -/-
AHCY-19 rs819171 C TT -/-
BHMT R239Q rs3733890 A GG -/-
BHMT-02 rs567754 T TT +/+
BHMT-08 rs651852 T TT +/+
CBS A13637G rs2851391 T CT +/-
CBS A360A rs1801181 A AG +/-
CBS C19150T rs4920037 A GG -/-
CBS C699T rs234706 A GG -/-
CLCN6 rs13306560 T CC -/-
COMT rs6269 G GG +/+
COMT -61 P199P rs769224 A GG -/-
COMT H62H rs4633 T CC -/-
COMT V158M rs4680 A GG -/-
DAO rs2070586 A AG +/-
DAO rs3741775 C AC +/-
DHFR rs1643649 C TT -/-
FOLR1 rs2071010 A GG -/-
FOLR2 rs651933 G AG +/-
FOLR3 rs7925545 G AA -/-
FUT2 rs492602 G AG +/-
FUT2 rs601338 A AG +/-
FUT2 rs602662 A AG +/-
G6PD rs1050828 T C –
G6PD rs1050829 C T –
GAD1 rs10432420 A GG -/-
GAD1 rs12185692 A AC +/-
GAD1 rs2058725 C CT +/-
GAD1 rs2241165 C CT +/-
GAD1 rs3749034 A AG +/-
GAD1 rs3791850 A AG +/-
GAD1 rs3791851 C TT -/-
GAD1 rs3791878 T GG -/-
GAD1 rs3828275 T CT +/-
GAD1 rs701492 T CC -/-
GAD1 rs769407 C GG -/-
GAMT rs17851582 A AG +/-
GAMT rs55776826 T CT +/-
GIF rs558660 A AG +/-
MAOA R297R rs6323 T T +/+
MTHFD1 C105T rs1076991 T TT +/+
MTHFD1 G1958A rs2236225 A AG +/-
MTHFD1L rs11754661 A AA +/+
MTHFD1L rs17349743 C CT +/-
MTHFD1L rs6922269 A GG -/-
MTHFD1L rs803422 A GG -/-
MTHFR rs1476413 T CC -/-
MTHFR rs17037390 A GG -/-
MTHFR rs4846049 T GG -/-
MTHFR (LOC100506310) rs4846048 G AA -/-
MTHFR 03 P39P rs2066470 A GG -/-
MTHFR A1298C rs1801131 G TT -/-
MTHFR A1572G rs17367504 G AA -/-
MTHFR C677T rs1801133 A AG +/-
MTHFR G1793A (R594Q) rs2274976 T CC -/-
MTHFS rs6495446 T CC -/-
MTR A2756G rs1805087 G AA -/-
MTRR A66G rs1801394 G GG +/+
MTRR K350A rs162036 G AA -/-
MTRR-11 A664A rs1802059 A GG -/-
NOS2 rs2248814 A AG +/-
NOS2 rs2274894 T GT +/-
NOS2 rs2297518 A AG +/-
NOS3 rs1800779 G AA -/-
NOS3 rs1800783 A TT -/-
PEMT rs4244593 T GT +/-
SOD2 rs2758331 A AA +/+
SOD2 rs4880 G GG +/+
SOD3 rs2855262 C CC +/+
TCN1 rs526934 G AG +/-
TCN2 C766G rs1801198 G GG +/+
VDR Bsm rs1544410 T CT +/-
VDR Taq rs731236 G AG +/-
My serotonin remains too long in the synapse and is converted into melatonin. Or is it something else?
I tried Methyl B12 and TMG but this makes my problem worse. I think I’m over methylated.
CBS: I’m not sensitive to sulfur.
Diet: paleo
I now use 1x Hydroxy B12 10.000ug
2x 400mcg Methylfolate
1x zinc 50mg
3 vit c 3000mg
1x vit d 5000
1x vit e 400
6x magnesium 200mg
2x molybdenum 100
What to do about the adrenalin and delta dominance?
ACAT1 rs3741049 A AG +/-
ACE Del16 rs4343 G AG +/-
AGT M235T/C4072T rs699 A AG +/-
AHCY-01 rs819147 C TT -/-
AHCY-19 rs819171 C TT -/-
BHMT R239Q rs3733890 A GG -/-
BHMT-02 rs567754 T TT +/+
BHMT-08 rs651852 T TT +/+
CBS A13637G rs2851391 T CT +/-
CBS A360A rs1801181 A AG +/-
CBS C19150T rs4920037 A GG -/-
CBS C699T rs234706 A GG -/-
CLCN6 rs13306560 T CC -/-
COMT rs6269 G GG +/+
COMT -61 P199P rs769224 A GG -/-
COMT H62H rs4633 T CC -/-
COMT V158M rs4680 A GG -/-
DAO rs2070586 A AG +/-
DAO rs3741775 C AC +/-
DHFR rs1643649 C TT -/-
FOLR1 rs2071010 A GG -/-
FOLR2 rs651933 G AG +/-
FOLR3 rs7925545 G AA -/-
FUT2 rs492602 G AG +/-
FUT2 rs601338 A AG +/-
FUT2 rs602662 A AG +/-
G6PD rs1050828 T C –
G6PD rs1050829 C T –
GAD1 rs10432420 A GG -/-
GAD1 rs12185692 A AC +/-
GAD1 rs2058725 C CT +/-
GAD1 rs2241165 C CT +/-
GAD1 rs3749034 A AG +/-
GAD1 rs3791850 A AG +/-
GAD1 rs3791851 C TT -/-
GAD1 rs3791878 T GG -/-
GAD1 rs3828275 T CT +/-
GAD1 rs701492 T CC -/-
GAD1 rs769407 C GG -/-
GAMT rs17851582 A AG +/-
GAMT rs55776826 T CT +/-
GIF rs558660 A AG +/-
MAOA R297R rs6323 T T +/+
MTHFD1 C105T rs1076991 T TT +/+
MTHFD1 G1958A rs2236225 A AG +/-
MTHFD1L rs11754661 A AA +/+
MTHFD1L rs17349743 C CT +/-
MTHFD1L rs6922269 A GG -/-
MTHFD1L rs803422 A GG -/-
MTHFR rs1476413 T CC -/-
MTHFR rs17037390 A GG -/-
MTHFR rs4846049 T GG -/-
MTHFR (LOC100506310) rs4846048 G AA -/-
MTHFR 03 P39P rs2066470 A GG -/-
MTHFR A1298C rs1801131 G TT -/-
MTHFR A1572G rs17367504 G AA -/-
MTHFR C677T rs1801133 A AG +/-
MTHFR G1793A (R594Q) rs2274976 T CC -/-
MTHFS rs6495446 T CC -/-
MTR A2756G rs1805087 G AA -/-
MTRR A66G rs1801394 G GG +/+
MTRR K350A rs162036 G AA -/-
MTRR-11 A664A rs1802059 A GG -/-
NOS2 rs2248814 A AG +/-
NOS2 rs2274894 T GT +/-
NOS2 rs2297518 A AG +/-
NOS3 rs1800779 G AA -/-
NOS3 rs1800783 A TT -/-
PEMT rs4244593 T GT +/-
SOD2 rs2758331 A AA +/+
SOD2 rs4880 G GG +/+
SOD3 rs2855262 C CC +/+
TCN1 rs526934 G AG +/-
TCN2 C766G rs1801198 G GG +/+
VDR Bsm rs1544410 T CT +/-
VDR Taq rs731236 G AG +/-