frozenborderline
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I'm going to use this thread to try and compile all of the theory about thyroid that i've seen that may be pertinent to CFS.
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I just edited the posts to be a little betterWill you add summaries or excerpts under the links too, so it's more accessible to people with bad fatigue and cognitive issues?
CORE ARGUMENThttps://www.lesswrong.com/posts/9yK...ness-core-argument-evidence-probabilities-and
This is an argument about why CFS and related illnesses could be due to underdiagnosed thyroid issues that don't show up in blood tests. It goes through the history of thyroid diagnoses and how doctors stop diagnosing based on pulse and temp. It makes an argument that the blood tests could be unreliable and that thyroid resistance needs to be taken into account. It connects the switch from diagnosing based on pulse and temp to the time frame in which CFS first emerged in the US.
To be honest I don't see that it is correct to just concentrate on the thyroid. The adrenals have to be strong in order for the thyroid to function as it should and in the past studies have shown a degree of low normal levels of cortisol in patients with CFS (as they called it then though I hate that term).
At the moment I am in an adrenal crash caused through the effects of high dose vitamin C recommended to me by a certain well known ME doctor and my temperature has plummeted and I feel cold and have all the symptoms of hypothyroidism/ME back but I hadn't changed my usual thyroid medication that I have been taking for over 15 years and normally keeps me fairly well. My adrenals have caused this after weeks of a gut bug/migraines and intolerance to so much citric acid.
However back to the topic of this thread, one has to be very careful in trying to push thyroid meds up when the adrenals are weak, you just end up with more undesirable side effects that can feel horrible. It has to be done slowly and gradually which can be very frustrating but one has to work with the weak adrenals too.
I agree that so many of the symptoms of ME/CFS are the same as hypothyroidism and for me they definitely go together.
Pam
Do we burn out because of the overdose of adrenaline?
I agree this may be reductive, and I am also interested in theories like Naviaux's that focus on a more complex etiology (purinergic signalling).My illness may include thyroid, but it encompasses so much more, like my immune system, mitochondria, nervous system, etc.
Tweaking the endocrine system to function well is helpful in recovery, but one must look at what's throwing it off in the first place.
for example, even if someone doesn't respond to standard thyroid treatment, it might not be an indicator that they don't have thyroid issues. the t1am theory in particular discusses complex thyroid resistanceI agree this may be reductive, and I am also interested in theories like Naviaux's that focus on a more complex etiology (purinergic signalling).
But thyroid is upstream of a lot of things, and I am curious about the theories (that I admit are a little kooky) that focus on thyroid issues as the root of a lot of disorders. The piece by John Lawrence aspden?? that I posted is particularly interesting, because he posted it on a rationalist forum that's certainly populated by skeptics, and he presents the arguments with a lot of logical formulas , etc.
I by no means know what the cause of CFS is. Some of the stuff about thyroid issues being not diagnosable by blood test, the role of T1AM, and thyroid hormone resistance would all help explain some ME/CFS symptoms though.
I meant to explain more of that in this thread, but it was kind of an ambitious undertaking and I'm not feeling that great rn.