http://web.mac.com/thriiive/THRiiiVE_New/Stuff/Entries/2010/6/22_The_"Vinitsky_Protocol"__.html This is s presentation given by Dr V as well as the pdf. Very interesting and would love to hear comments. He is addressing ANS imbalance by scavenging aldehydes and glutatmates with a sublingual form of hydroxy B12 and folic acid in a 5:2 ratio FA to HB12. This is called "cleaning up stress". The claims are that once the stress is cleaned up, folks can tolerate supplements and therapies they could not before. I have made it through the presentation: videos 1-12 and am still to view the question, answer session, videos 13-14. My Questions so far: (1) What about CBS upregulation and draining the transsulfuration pathway? (2) Is it possible to overpush methylation with the continual high doses of the 5:2 (6-30/40 a day!) and the use of methionine? (3) Methyalted form of FA is used for folks who are MTHFr++. Is there are potential problem with the FA forms competing in the cells for methylation? Is there a problem using only FA and when exactly does FA become methylated? (4) FA loses glutamates when it is methylated, I believe. How does the body determine how much FA to methylate? Dr V says first priority of the body is to clean up stress.. before methylation. Im wondering about FA losing glutamates which would create a repeating cycle of picking up and dropping. (5) Do you pass FA in the urine with glutatmates and aldehydes attached? (6) What happens to aldehydes. I think I read in another publication by Dr V that aldehydes are passed to HB12 for another purpose.. I'll look that up. (7) What happens to blood/serum levels of FA and cellular levels? (8) What are the methylation markers.. this is mentioned in the presentation and I think the measures are different from Rich's and Dr Amys. Thanks!!