I realize a one size fits all approach doesn't work because everyone is different. However, if we are targeting a specific SNP or combination of SNP's, I don't see why it can't be utilized. I had an appointment with Dr. Rind yesterday, and his protocol for MTHFR (I'm compound heterozygous), is Methylguard Plus. I looked at the ingredients and it looks quite good. It seems like a high dose if you've never titrated up before, and it lacks Freddd's LCF, and ADB12, but it seems to have everything else and more. http://www.pureformulas.com/methylg...L8CFaTm7Aod-UYA8A&CA_6C15C=530005240000828477 Thoughts?