International ME/CFS and FM Awareness Day Is On May 12, 2018
Thomas Hennessy, Jr., selected May 12th to be our international awareness day back in 1992. He knew that May 12th had also been the birthday of Florence Nightingale. She was the English army nurse who helped to found the Red Cross as well as the first school of nursing in the world.
Discuss the article on the Forums.

[Sweden] Opinion piece: B12/B9 – possible treatment for mental fatigue

Discussion in 'General ME/CFS News' started by mango, Jul 11, 2017.

  1. mango

    mango Senior Member

    An opinion piece in Läkartidningen (Swedish website for doctors), written by professor emeritus Björn Regland: "Vitamin B12/B9 -- possible treatment for mental fatigue"

    Vitamin B12/B9 – möjlig behandling vid mental trötthet

    ETA references:

    1. Ellis FR, Nasser S. A pilot study of vitamin B12 in the treatment of tiredness. Br J Nutr. 1973;30(2):277-83.
    2. Brenu EW, Staines DR, Marshall-Gradisnik SM. Methylation profile of CD4+ T cells in chronic fatigue syndrome/myalgic encephalomyelitis. J Clin Cell Immunol. 2014;5:228.
    3. De Vega WC, Vernon SD, McGowan PO. DNA methylation modifications associated with chronic fatigue syndrome. PLoS One. 2014;9(8):e104757.
    4. Naviaux RK, Naviaux JC, Li K, et al. Metabolic features of chronic fatigue syndrome. Proc Natl Acad Sci U S A. 2016;113(37):E5472-80.
    5. Regland B, Andersson M, Abrahamsson L, et al. Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome. Scand J Rheumatol. 1997;26(4):301-7.
    6. Regland B, Forsmark S, Halaouate L, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10(4):e0124648.
    Last edited: Jul 11, 2017
  2. PinkPanda

    PinkPanda Senior Member

    I have the biggest benefits from sublingual hydroxocobalamin, I don't have that good reactions to other b12 forms. It makes me feel that sufficient hydroxocobalamin intake is important. Don't know if it would make a difference to get injections.
    And I can also agree that it's a helpful combination taking b12 and methylfolate. I don't have good reactions to taking b6 or amino acids though.
    This text does confirm that methylation and homocysteine are important issues to look at.
    trishrhymes likes this.

See more popular forum discussions.

Share This Page