Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Suppressing B Cells vs Depleting them

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by AdamS, May 13, 2017.

  1. AdamS

    AdamS Senior Member

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    This could be a completely silly question so apologies in advance, but given that a number of responding ME patients treated with Rituximab report improvements followed by relapse when their B cells come back, are there any drugs out there that could:

    • Suppress circulating B cells to a point where clinical improvement is seen.
    • Disrupt B cell signalling somehow.
    • Do something else to B cells that might benefit us.
    All replies greatly appreciated!
     
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  2. Cheesus

    Cheesus Senior Member

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    I am sure my answer will be overshadowed by someone with far superior knowledge, however one method that might be useful is to attempt to boost regulatory B-cells somehow. These are part of the body's natural immune suppression mechanism.
     
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  3. Jesse2233

    Jesse2233 Senior Member

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    Rapamycin is one drug that comes to mind
     
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  4. deleder2k

    deleder2k Senior Member

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