Hi everyone, So I am still undiagnosed after many tests and in the moderate-to-severe symptom range. My symptoms overlap about 80% with ME/CFS, but the quality and variability of the brain fog I experience is a significant difference. And the most bizarre part is that it is dramatically affected by probiotics and cultured foods. Whenever I take probiotics or eat certain cheeses, yogurt, etc., after 15-30 minutes I get a gradual feeling of being drugged up. This sensation continues to worsen over the next several hours, and can take a couple days to fully wear off. If I manage to avoid these foods, I still have a moderate level background of brain fog, fatigue, etc. but it doesn't spike suddenly; it's fairly stable. But it's still significantly disabling. I've speculated about gut dysbiosis. First I considered candida, and managed to get prescribed an antifungal, but it had no effect. I've also read up on SIBO, but I don't have bloating, belching, or other digestive issues. Wouldn't this rule SIBO out? Recently I got tested for mycoplasma, still waiting on the results. I'm fairly sure it's not celiac disease because I even have this reaction with probiotic pills, and I never have it after eating bread or pasta. I've also tried elimination diets (no dairy, no sugar, no gluten, etc.) with no effect. Could this be some other type of bacterial infection? Something auto-immune? My ANA was tested and was negative, along with the standard CBC tests. I'm currently getting my IgG, IgA, and IgM levels tested. I'm really at a loss of what to do next. My only other idea would be to try an antibiotic to see if it had any effect. But what baffles me is that even after countless hours searching the Internet, I haven't been able to find anyone else who's experienced this set of symptoms and reactions. I can find no medical documentation of this. Auto-fermentation syndrome is pretty similar but it involves feeling drunk and the culprit is yeast, which would been cleared by the anti-fungal. The sensation I experience is much more like a narcotic than alcohol (I can say this because I've drunk alcohol and took Vicodin after a surgery years ago). Please let me know if you guys have any ideas for further tests, treatments, or conditions that I should consider. Thanks!