Well, I tried it. After one week of being on Valcyte, I'm stopping it. Will see what happens. I was on such a small dose. 1/16 of a pill. I started having horrible pain in my hands that would wake me up two hours after going to bed. Every single night this is happening. Now, I suffer with fibromyalgia and Sjogrens syndrome, but I've never had this before. It's been making sleep almost impossible. Tonight I went to bed and the same thing happened and today I've had the worst pain I've had since my wrist surgery. I've had pain all over my body. I got up at 3 am and thought.... Something is doing this. This is NOT me. Stopping Valcyte. This isn't completely shocking since every antiviral medicine affects me with arthritis like pain. The Acyclovir caused my hands to curl up into a claw and I had pins and needles in my hands. Will report in a week or less if I'm better. I'm hoping it is the med so it will stop and fast! The soles of my feet were also hurting. Gosh! Strike out!