Yesterday I had my first infusion and I take it again early January (about 2 weeks from my first dose). So far, it's gone fairly smoothly. No allergic response to the infusion. The only negative aspect was felt very cold from the saline infusion; was not prepared for how uncomfortable that was going to be; will be more prepared next time. Otherwise, just used my iPad during the 5 hours and slept during much of it because of the benadryl they give to protect against allergic response. I understand most don't feel anything for 1-2 weeks and usually by 6 weeks and so far from me nothing yet. Yes I heard about the Oslo results but I will wait to hear more details; Chronic Fatigue comes in many forms and it's possible that some respond and other's don't. I will post again on this thread with updates. Welcome any input from those who've been on Rituxan.