Well, keep researching and trying. Sometimes it take a long time to come up with all the answers. Personally I think the low BH4 with MTHFR 1298 must be correct because my husband has it (one copy) without the MAO A mutation (so he gets rid of serotonin at a normal rate) and he has had mild depression all his life, enough to interfere with his enjoyment of life, but it doesn't stop his motivation and he feels great with only mg of 5-htp a day.
I hope you find all your answers soon!
I hope you find all your answers soon!