After being out of options in the Netherlands (where I live), I went to see dr. Kenny de Meirleir in Belgium. He diagnosed me with SIBO and said that my symptoms (mostly fatigue and skin rash) are caused by LPS (lipopolysacharoids). He concluded high LPS because sCD14, which he says is a surrogate marker for LPS, is increased. Also IL-6 and IL-8 are increased. He concluded that my intestinal permeability is increased because I have higher levels of Zonulin in my faeces. And the analysis of my gut bacteria show a high percentage of anaerobes. Particularly, a high percentage of bacteroids and alistipes, a high percentage of Clostridium IV/XIVb, and Parasutterella, and a low percentage Bifidobacterium. Basically, I don't know what most of this means, so I'm wondering if the conclusions he draws make sense to someone who is more knowledgeable than me. Based on these results I started treatment 2 months ago. The treatment consisted of the following for 8 weeks: - Flagyl 500 mg (an antibiotic), twice a day for 6 days, followed by 8 days of Bififlor (a probiotic) twice a day. Doing this 4 times. - Hydroxycobalamine 10 mg (Vit B12) twice a week (injection) - Choline-DHA twice a day - Toxaprevent 2 tablets before every meal 3 times a day - Gammanorm 165 mg/ml, 6 ml, once a week (injection) - Allegratab one tablet every morning The 8 weeks are almost over now, and so far I haven't felt any improvement (it hasn't gotten worse either). Next week I'm going to see KDM again, so I'm wondering if there are people here who have advice about particular treatments that I could ask him about. Because he's not a very talkative man so I want to really go there well prepared so I can get all the information I need out of him. Personally, I was wondering why he didn't prescribe me rifaximin as an antibiotic, because I read this is most often used to treat SIBO. Also I'm wondering if a faeces transplant would be helpful as a treatment. Any thoughts on this? Also I'm wondering what people think about the treatment I'm currently getting. Are there people who received a similar treatment for whom it worked?